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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2584 | Octreotide | SMS 201-995 | Somatostatin |
Octreotide (SMS 201-995) is a potent inhibitor of growth hormone, glucagon, and insulin. | |||
T11798 | L-692429 | MK-0751 | GHSR , GPCR19 |
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G prot... | |||
T39262L | BIM-23190 aceate | Somatostatin | |
BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies. | |||
T9692 | Paltusotine | Somatostatin | |
Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients | |||
T20534 | Lanreotide | BIM 23014,Somatulin,Lanreotide Autogel,Somatuline,Ipstyl | |
Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours. | |||
T39262 | BIM-23190 | ||
BIM-23190 is a somatostatin analog that acts as a selective agonist for SSTR2 and SSTR5 receptors. It displays potency with K i values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 finds utility in ... | |||
T37109 | BIM-23190 hydrochloride | ||
BIM-23190 hydrochloride, a selective agonist for somatostatin receptors SSTR2 and SSTR5 with Ki values of 0.34 nM and 11.1 nM respectively, is a somatostatin analog utilized in research on cancer and acromegaly[1][3]. | |||
T75157 | Cimdelirsen | ||
Cimdelirsen, a novel ligand-conjugated, hepatic-targeted antisense oligonucleotide under investigation, aims to diminish growth hormone receptor (GHr) synthesis. This inhibits the harmful effects of growth hormone (GH) h... | |||
T75157L | Cimdelirsen sodium | ||
Cimdelirsen sodium is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor synthesis. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00806 | GHR/Growth Hormone R Protein, Human, Recombinant (His) | Human | HEK293 |
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual f... |