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c-Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T77939 WBC100 2095780-08-6 98%
WBC100
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway,...
T78055 MYC-RIBOTAC 98%
MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered t...
T78986 MDEG-541 98%
MDEG-541
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].
T79438 C-Myc inhibitor 11 98%
c-Myc inhibitor 11
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat ph...
T79439 C-Myc inhibitor 12 98%
c-Myc inhibitor 12
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].
T79872 M-Se3 2829939-44-6 98%
m-Se3
m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
T40419 IRES-C11 342416-30-2 98%
IRES-C11
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
TN3708 Coronarin D 119188-37-3 98%
Coronarin D
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
TN2177 Sanggenol L 329319-20-2 98%
Sanggenol L
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
TN4582 Moracin T 1146113-27-0 98%
Moracin T
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
T16839 SAJM589 2089-82-9 98%
sAJM589
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
T11783 KSI-3716 1151813-61-4 98%
KSI-3716
KSI-3716 is an inhibitor of c-Myc.
TN1354 Aaptamine 85547-22-4 98%
Aaptamine
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T10702 CBP/p300-IN-2 2158265-96-2 98%
CBP/p300-IN-2
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
TN4581 Moracin D 69120-07-6 98%
Moracin D
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
T60019 VPC-70063 13571-44-3 99.93%
VPC-70063
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inh...
T0617 Nicotinamide N-oxide 1986-81-8 99.9%
Nicotinamide N-oxide
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
T3048 10058-F4 403811-55-2 99.82%
10058-F4
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target g...
T9093 NY2267 886053-73-2 99.6%
NY2267
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester...
T4367 Mycro 3 944547-46-0 99.51%
Mycro 3
Mycro 3 is potent and selective for c-Myc in whole cell assays.
WBC100
T77939
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway,...
MYC-RIBOTAC
T78055
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered t...
MDEG-541
T78986
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].
c-Myc inhibitor 11
T79438
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat ph...
c-Myc inhibitor 12
T79439
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].
m-Se3
T79872
m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
IRES-C11
T40419
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
Coronarin D
TN3708
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
Sanggenol L
TN2177
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
Moracin T
TN4582
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
sAJM589
T16839
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
KSI-3716
T11783
KSI-3716 is an inhibitor of c-Myc.
Aaptamine
TN1354
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
CBP/p300-IN-2
T10702
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
Moracin D
TN4581
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
VPC-70063
T60019
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inh...
Nicotinamide N-oxide
T0617
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
10058-F4
T3048
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target g...
NY2267
T9093
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester...
Mycro 3
T4367
Mycro 3 is potent and selective for c-Myc in whole cell assays.
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