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Virus Protease

Virus protease or 3C protease are virus cysteine proteases which have essential role in viral replication. The protease cleaves the precursor viral polyprotein to produce functional proteins and enzymes.Virus proteases are attractive target for therapeutic agents for treatment of diseases caused by the common cold virus.Viral protease - a Cys protease fold is similar to that of trypsin-like serine proteases. The active site triad contains Cys147, His40 and Glu71 (PDB entry 1cqq).
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T6S1315 Oroxylin A 480-11-5 99.67%
Oroxylin A
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses...
T0188 Fluticasone (propionate) 80474-14-2 99.65%
Fluticasone (propionate)
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid recep...
T2741 Glycyrrhizic acid 1405-86-3 99.62%
Glycyrrhizic acid
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
T25770 116-9e 831217-43-7 99.55%
116-9e
116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibition of simian virus 40 (SV40) replication, inhibition of tumo...
T9957 LASV inhibitor 3.3 554438-52-7 99.55%
LASV inhibitor 3.3
LASV inhibitor 3.3 is an inhibitor of Lassa fever virus (LASV) targeting lysosome-associated membrane protein 1 (LAMP1), a host factor that binds to the LASV gly...
TN2111 Prunin 529-55-5 99.52%
Prunin
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate g...
T2774 Lycorine hydrochloride 2188-68-3 99.49%
Lycorine hydrochloride
Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
T72041 Flaviviruses-IN-2 1009762-84-8 99.44%
Flaviviruses-IN-2
Flaviviruses-IN-2 is a potent flaviviruses inhibitor. Flaviviruses-IN-2 reduces West Nile virus (WNV) protease activity and inhibits WNV by 56%.
T4061 LY2334737 892128-60-8 99.4%
LY2334737
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T67777 Flaviviruses-IN-3 420090-97-7 99.39%
Flaviviruses-IN-3
Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibiti...
T0825 Ebselen 60940-34-3 99.38%
Ebselen
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimet...
T72051 LabMol-319 381188-63-2 99.36%
LabMol-319
LabMol-319 is a potent Zika virus (ZIKV) NS5 RdRp inhibitor with antiviral activity for the study of ZIKV virus.
T16809 Rupintrivir 223537-30-2 99.35%
Rupintrivir
Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirv...
T5013 Brequinar 96187-53-0 99.21%
Brequinar
Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
TMO2787 Anthraquinone 84-65-1 99.2%
Anthraquinone
Anthraquinone (Anthradione)s are the main active constituents in herbs often used to relieve constipation.
T0495 Aminothiazole 96-50-4 99.18%
Aminothiazole
Aminothiazole (2-Aminothiazole), a thyroid inhibitor, displays antibacterial activity.
T16914 SP187 615253-61-7 99.18%
SP187
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.
T8498 EIDD-1931 3258-02-4 99.14%
EIDD-1931
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus...
T3759 3,4-Dimethoxycinnamic acid 2316-26-9 99.07%
3,4-Dimethoxycinnamic acid
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exert...
T0800 Danthron 117-10-2 99.03%
Danthron
Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
Oroxylin A
T6S1315
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses...
Fluticasone (propionate)
T0188
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid recep...
Glycyrrhizic acid
T2741
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
116-9e
T25770
116-9e (MAL2-11B) is a potent Hsp70 co-chaperone DNAJA1 inhibitor with antiviral properties, inhibition of simian virus 40 (SV40) replication, inhibition of tumo...
LASV inhibitor 3.3
T9957
LASV inhibitor 3.3 is an inhibitor of Lassa fever virus (LASV) targeting lysosome-associated membrane protein 1 (LAMP1), a host factor that binds to the LASV gly...
Prunin
TN2111
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate g...
Lycorine hydrochloride
T2774
Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
Flaviviruses-IN-2
T72041
Flaviviruses-IN-2 is a potent flaviviruses inhibitor. Flaviviruses-IN-2 reduces West Nile virus (WNV) protease activity and inhibits WNV by 56%.
LY2334737
T4061
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
Flaviviruses-IN-3
T67777
Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibiti...
Ebselen
T0825
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimet...
LabMol-319
T72051
LabMol-319 is a potent Zika virus (ZIKV) NS5 RdRp inhibitor with antiviral activity for the study of ZIKV virus.
Rupintrivir
T16809
Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirv...
Brequinar
T5013
Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
Anthraquinone
TMO2787
Anthraquinone (Anthradione)s are the main active constituents in herbs often used to relieve constipation.
Aminothiazole
T0495
Aminothiazole (2-Aminothiazole), a thyroid inhibitor, displays antibacterial activity.
SP187
T16914
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.
EIDD-1931
T8498
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus...
3,4-Dimethoxycinnamic acid
T3759
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exert...
Danthron
T0800
Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
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TargetMol