Home Tools
Log in
Cart

VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T29797 AKB-6899 1007377-55-0 97.11%
AKB-6899
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macr...
T5164 Cabozantinib hydrochloride 1817759-42-4 97.09%
Cabozantinib hydrochloride
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM...
T6458 CYC-116 693228-63-6 96.6%
CYC-116
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active a...
T35570 Chiauranib 1256349-48-0 96.25%
Chiauranib
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related k...
T15185 Lucitanib 1058137-23-7 96.13%
Lucitanib
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, ...
T2056 VEGFR-2-IN-5 1430089-64-7 81.14%
VEGFR-2-IN-5
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
T6184 Orantinib 252916-29-3 100%
Orantinib
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It ...
T8402 Regorafenib Hydrochloride 835621-07-3 100%
Regorafenib Hydrochloride
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with pote...
T23554 (Z)-FeCP-oxindole 1137967-28-2 100%
(Z)-FeCP-oxindole
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.
T6720 Vatalanib dihydrochloride 212141-51-0 100%
Vatalanib dihydrochloride
Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against...
T22432 SU5208 62540-08-3 100%
SU5208
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).
T60094 SU 4981 186610-88-8 100%
SU 4981
SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.
T2372L Ponatinib Hydrochloride 1114544-31-8 100%
Ponatinib Hydrochloride
Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.3...
T7104 Dovitinib lactate 692737-80-7 100%
Dovitinib lactate
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
T0342 Carvedilol phosphate hemihydrate 610309-89-2 100%
Carvedilol phosphate hemihydrate
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
T13157 TG 100801 867331-82-6 100%
TG 100801
TG 100801 is a dual inhibitor of VEGFr2 and Src family (Src and YES) kinases and is a candidate compound for the treatment of age-related macular degeneration (A...
T1936 Alectinib 1256580-46-7
Alectinib
Alectinib (RG-7853) is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity.
T8491 Vorolanib 1013920-15-4
Vorolanib
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
TQ0317 R1530 882531-87-5
R1530
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T14943 CGP60474 164658-13-3
CGP60474
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits ...
AKB-6899
T29797
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macr...
Cabozantinib hydrochloride
T5164
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM...
CYC-116
T6458
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active a...
Chiauranib
T35570
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related k...
Lucitanib
T15185
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, ...
VEGFR-2-IN-5
T2056
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
Orantinib
T6184
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It ...
Regorafenib Hydrochloride
T8402
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with pote...
(Z)-FeCP-oxindole
T23554
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.
Vatalanib dihydrochloride
T6720
Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against...
SU5208
T22432
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).
SU 4981
T60094
SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.
Ponatinib Hydrochloride
T2372L
Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.3...
Dovitinib lactate
T7104
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
Carvedilol phosphate hemihydrate
T0342
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
TG 100801
T13157
TG 100801 is a dual inhibitor of VEGFr2 and Src family (Src and YES) kinases and is a candidate compound for the treatment of age-related macular degeneration (A...
Alectinib
T1936
Alectinib (RG-7853) is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity.
Vorolanib
T8491
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
R1530
TQ0317
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
CGP60474
T14943
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits ...
1 2 3 4 5 6 7 8 9 10 11 12
TargetMol