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Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN1832 Kanzonol C 151135-82-9 98%
Kanzonol C
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
TN1690 Glabrene 60008-03-9 98%
Glabrene
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
TN4179 Haginin A 74174-29-1 98%
Haginin A
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
TN1958 Mulberroside F 193483-95-3 98%
Mulberroside F
Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity tha...
TN4279 Isoderrone 121747-89-5 98%
Isoderrone
Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, sugge...
TN2026 Oxyresveratrol 3'-O-β-D-glucopyranoside 144525-40-6 98%
Oxyresveratrol 3'-O-β-D-glucopyranoside
Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any seri...
TN3882 Dodoviscin A 1372527-25-7 98%
Dodoviscin A
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
TN4117 GB 1a 220611-41-6 98%
GB 1a
GB 1a is a natural product isolated from the leaves of Garcinia travancorica.
TMA2563 Pedalitin 22384-63-0 98%
Pedalitin
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosm...
TN3753 Dalbergioidin 30368-42-4 98%
Dalbergioidin
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...
TN2923 3'-Deoxy-4-O-methylsappanol 112408-68-1 98%
3'-Deoxy-4-O-methylsappanol
3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.
TN3545 Buddlenoid A 142750-32-1 98%
Buddlenoid A
Buddlenoid A shows high inhibition of mushroom tyrosinase.
TMA0593 Broussoflavonol F 162558-94-3 98%
Broussoflavonol F
Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
TN2698 2,3-Dihydroisoginkgetin 828923-27-9 98%
2,3-Dihydroisoginkgetin
2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.
TN2025 Oxyresveratrol 2-O-β-D-glucopyranoside 392274-22-5 98%
Oxyresveratrol 2-O-β-D-glucopyranoside
Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
TN5119 Taxoquinone 21764-41-0 98%
Taxoquinone
Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important food...
TN5153 Torilin 13018-10-5 98%
Torilin
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
TN4148 Glyasperin C 142474-53-1 98%
Glyasperin C
Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidat...
TMA0003 Trans-caffeic acid 501-16-6 98%
Trans-caffeic acid
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
T1188 Mizoribine 50924-49-7 99.98%
Mizoribine
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Kanzonol C
TN1832
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
Glabrene
TN1690
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
Haginin A
TN4179
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
Mulberroside F
TN1958
Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity tha...
Isoderrone
TN4279
Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, sugge...
Oxyresveratrol 3'-O-β-D-glucopyranoside
TN2026
Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any seri...
Dodoviscin A
TN3882
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
GB 1a
TN4117
GB 1a is a natural product isolated from the leaves of Garcinia travancorica.
Pedalitin
TMA2563
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosm...
Dalbergioidin
TN3753
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...
3'-Deoxy-4-O-methylsappanol
TN2923
3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.
Buddlenoid A
TN3545
Buddlenoid A shows high inhibition of mushroom tyrosinase.
Broussoflavonol F
TMA0593
Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
2,3-Dihydroisoginkgetin
TN2698
2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.
Oxyresveratrol 2-O-β-D-glucopyranoside
TN2025
Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
Taxoquinone
TN5119
Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important food...
Torilin
TN5153
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
Glyasperin C
TN4148
Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidat...
Trans-caffeic acid
TMA0003
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
Mizoribine
T1188
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
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TargetMol