Transferase

A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.

Cat. No.	Product name	CAS No.	Purity
T11016	DGAT-1 inhibitor 2	942999-61-3	98.27%
T11016	DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known ...
T27691	JNJ-DGAT2-A	1962931-71-0	98.2%
T27691	JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.
T2765	Rosmarinic acid	20283-92-5	98.19%
T2765	Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and C...
T2700	FTI-277 hydrochloride	180977-34-8	98.19%
T2700	FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
T1599L	Ibandronate sodium	138844-81-2	98.13%
T1599L	Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
T7439	3-Methoxybenzamide	5813-86-5	98%
T7439	3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
T6302	Lonafarnib	193275-84-2	98%
T6302	Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
T8489	Minodronic acid monohydrate	155648-60-5	98%
T8489	Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
T4473	Ibiglustat	1401090-53-6	97.97%
T4473	Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation o...
T6365	A 922500	959122-11-3	97.66%
T6365	A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
T1455	Nialamide	51-12-7	93.91%
T1455	Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
T35626	AMP-Deoxynojirimycin	216758-20-2	100%
T35626	AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesi...
T16398	Opicapone	923287-50-7	100%
T16398	Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for ...
T10512	Prenyl-IN-1	360561-53-1	100%
T10512	Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects i...
T0525	Flopropione	2295-58-1	100%
T0525	Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
T25210	CBHcy	88096-02-0	100%
T25210	CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the t...
T38050	CP-609754	1190094-64-4
T38050	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombin...
T11282	FGTI-2734	1247018-19-4	98%
T11282	FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, r...
T4681	T863	701232-20-4	98%
T4681	T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
T6844	GGTI298 Trifluoroacetate	1217457-86-7	98%
T6844	GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...