TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T23004	ML-SA1	332382-54-4	99.28%
T23004	ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification a...
T9709	TRPM8 antagonist 3	2102179-29-1	99.25%
T9709	TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).
T12941	SN 2	823218-99-1	99.20%
T12941	SN 2 is a novel and potent TRPML3 ion channel activator(EC50 of 1.8±0.13 μM).
T27308	FEMA-4809	1374760-95-8	99.19%
T27308	FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception, which is triggered either by temperatures belo...
T16688	Pyr6	245747-08-4	99.18%
T16688	Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhi...
T6617	Optovin	348575-88-2	99.16%
T6617	Optovin is a TRPA1 activator, which is reversibly photoactivated.
T0647	Tryptamine	61-54-1	99.16%
T0647	Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It ...
T0399	Methyl salicylate	119-36-8	99.13%
T0399	Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain...
T70540	Pinokalant	149759-26-2	99.09%
T70540	Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves ...
T5479	AMG 333	1416799-28-4	99.08%
T5479	AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
T4028	ML329	19992-50-8	99.07%
T4028	ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.
T1407	(-)-Menthol	2216-51-5	99.01%
T1407	(-)-Menthol (Levomenthol) is a levo isomer of menthol, an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local a...
T28020	Mesendogen	864716-85-8	98.90%
T28020	Mesendogen is an inhibitor of TRPM6. Mesendogen alters magnesium homeostasis, promotes mesoderm and definitive endoderm differentiation.
T8449	TC-I2000	1159996-20-9	98.87%
T8449	TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.
T0882	(+)-Camphor	464-49-3	98.82%
T0882	(+)-Camphor (D-Camphor) is the oil extracted from the wood of the Camphor tree Cinnamomum Camphora with anti-inflammatory and analgesic properties.
T5640	GSK2193874	1336960-13-4	98.79%
T5640	GSK2193874 was identified as a selective, orally active TRPV4 blocker.
T9247	Vanilloid receptor antagonist 1	871814-52-7	98.77%
T9247	Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.
T72662	NMDAR/TRPM4-IN-2	2243506-33-2	98.77%
T72662	NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
T7177	Capsazepine	138977-28-3	98.76%
T7177	Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of c...
T9245	TRPM4-IN-1	351424-20-9	98.75%
T9245	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.