T39349 |
Vocacapsaicin hydrochloride
|
1931116-92-5
|
99.94%
|
|
Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.
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T15758 |
Linopirdine
|
105431-72-9
|
99.92%
|
|
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Lino...
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T6S1684 |
8-Gingerol
|
23513-08-8
|
99.92%
|
|
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Ging...
|
T0334 |
Rosiglitazone
|
122320-73-4
|
99.87%
|
|
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidi...
|
T13214L |
TRPV4 agonist-1 free base
|
2314467-59-7
|
99.86%
|
|
TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).
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T10929L |
D-3263 hydrochloride
|
1008763-54-9
|
99.85%
|
|
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
|
T2170 |
SKF-96365 hydrochloride
|
130495-35-1
|
99.85%
|
|
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells...
|
T2994 |
(E)-Cardamonin
|
19309-14-9
|
99.84%
|
|
(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel...
|
T8607 |
M084
|
51314-51-3
|
99.84%
|
|
M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.
|
T16483 |
PF-05105679
|
1398583-31-7
|
99.82%
|
|
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
|
T6646 |
Rosiglitazone hydrochloride
|
302543-62-0
|
99.79%
|
|
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
|
T3727 |
Methyl syringate
|
884-35-5
|
99.76%
|
|
Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic ac...
|
TN1927 |
Methyl Kakuol
|
70342-29-9
|
99.74%
|
|
Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 µM and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix.
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T10537 |
BI-749327
|
2361241-23-6
|
99.74%
|
|
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
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T12306 |
OMDM-5
|
616884-66-3
|
99.72%
|
|
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
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T29522 |
ABT 102
|
808756-71-0
|
99.72%
|
|
ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.
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T8442 |
M8-B Hydrochloride
|
883976-12-3
|
99.71%
|
|
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
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T7416 |
WS-12
|
68489-09-8
|
99.71%
|
|
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)
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T29968 |
AMG-0347
|
946615-43-6
|
99.7%
|
|
AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neuron...
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T16686 |
Pyr10
|
1315323-00-2
|
99.7%
|
|
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal in...
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