Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.

Cat. No.	Product name	CAS No.	Purity
T2173	Veratridine	71-62-5	99.27%
T2173	Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.
T0037	Halazone	80-13-7	90%
T0037	Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
TN3910	Ecdysone	3604-87-3	100%
TN3910	Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
T6782	Benzocaine hydrochloride	23239-88-5
T6782	Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at...
T3029	Sparteine sulfate	299-39-8
T3029	Sparteine sulfate (Tocosimplex) is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.
TN3042	4-Hydroxycinnamamide	194940-15-3	98%
TN3042	4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
T78060	ProTx II TFA		98%
T78060	ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over ot...
T78955	Analgesic agent-2		98%
T78955	Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human NaV1...
T79246	6-Iodoamiloride	60398-23-4	98%
T79246	6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM. It also effectively inhibits ASIC3-mediated curre...
T79280	Nav1.3 channel inhibitor 1		98%
T79280	Nav1.3 Channel Inhibitor 1 (Compound 15b) is a state-dependent inhibitor of the voltage-gated sodium channel Na v 1.3, with an IC50 value of 20 nM. It has the ab...
T79398	Ancistrotecine B		98%
T79398	Ancistrotecine B (Compound 2), a Nav1.7 channel inhibitor (IC50: 0.73 μM), has been shown to alleviate inflammatory pain in mice [1].
T79834	Aneratrigine	2097163-74-9	98%
T79834	Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].
T80039	ATX-II	60748-45-0	98%
T80039	ATX-II, an Na+ channel modulator toxin derived from the sea anemone (Anemonia sulcata), causes delayed inactivation of the Na+ channels and has been linked to pu...
T80042	GpTx-1	1661050-12-9	98%
T80042	GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].
T80043	µ-Conotoxin-CnIIIC	936616-33-0	98%
T80043	μ-Conotoxin-CnIIIC, a 22-residue conopeptide derived from Conus consors, acts as a potent and persistent NaV1.4 channel blocker, exhibiting analgesic, anaestheti...
T80049	µ-Conotoxin GIIIB	140678-12-2	98%
T80049	μ-Conotoxin GIIIB, a 22-residue polypeptide derived from the venom of the piscivorous cone snail Conus geographus, serves as an inhibitor of the Na V 1.4 channel...
T80159	µ-Conotoxin KIIIA	884469-67-4	98%
T80159	μ-Conotoxin KIIIA, an analgesic compound derived from Conus kinoshitai, selectively inhibits mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2), o...
T80162	Aah II		98%
T80162	Aah II, a sodium channel modulator, is a toxin derived from the venom of the scorpion Androctonus australis [1] [2].
T80163	μ-Conotoxin PIIIA	184840-20-8	98%
T80163	μ-Conotoxin PIIIA, isolated from Conus purpurascens [1] [2], is a blocker of the sodium channel NaV 1.4.
T80168	Scorpion toxin Tf2		98%
T80168	Scorpion toxin Tf2, a β-scorpion toxin first identified in the venom of the Brazilian scorpion Tityus fasciolatus, acts as an activator of the neuronal voltage-g...