Serine/threonin kinase

Serine threonine kinase belongs to protein kinase, which can phosphorylate the OH group of serine or threonine residues. Serine threonine kinases contain Rho kinase, Aurora kinase, AMP kinase, RAF kinase, Polo like kinase, PIM kinase, ATM kinase and other kinases. The cAMP/cGMP, Ca2+/calmodulin and diacylglycerol and multiple chenmical signals can regulate the activity of serine threonine kinases.

Cat. No.	Product name	CAS No.	Purity
TN2082	Pinostrobin	480-37-5	99.35%
TN2082	Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting...
T5194	SPHINX31	1818389-84-2	99.3%
T5194	SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
T2153	1-NM-PP1	221244-14-0	99.2%
T2153	1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T10572L	BMT-124110 Formate	T10572L	99.17%
T10572L	BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase ...
T27525	HA-1004	91742-10-8	99.03%
T27525	HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
T15781	LP-935509	1454555-29-3	99%
T15781	LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is also an effective inhibitor of BIKE (I...
T72025	PCSK9-IN-10	368434-98-4	98.85%
T72025	PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC5...
T13257	Upamostat	590368-25-5	98.8%
T13257	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
T77501	TAO Kinase inhibitor 2	850467-77-5	98.73%
T77501	TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
T24152	HTH-01-091	2000209-42-5	98.40%
T24152	HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
T19763	Cetraxate hydrochloride	27724-96-5	98.23%
T19763	Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.
T1863	CID 2011756	638156-11-3	98.15%
T1863	CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.
T7017	WNK463	2012607-27-9	98%
T7017	WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
T10547	BioE-1115	1268863-35-9	97.38%
T10547	BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
T2392	Nafamostat mesylate	82956-11-4	97.36%
T2392	Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and...
T2626	SBC-115076	489415-96-5	97.07%
T2626	SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T8676	FOY 251	71079-09-9	97.06%
T8676	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T36680	SM1-71	2088179-99-9	96%
T36680	SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3,...
T11666	IPR-803	892243-35-5	95%
T11666	IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM....
T5456	WNK-IN-11	2123489-30-3	100%
T5456	WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)