Home Tools
Log in
Cart

SARS-CoV

Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79515 SARS-CoV-2 Mpro-IN-10 98%
SARS-CoV-2 Mpro-IN-10
SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in res...
T79526 SARS-CoV-2 nsp14-IN-4 98%
SARS-CoV-2 nsp14-IN-4
SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 ...
T79570 SARS-CoV-2-IN-55 98%
SARS-CoV-2-IN-55
SARS-CoV-2-IN-55 (compound 65) is an inhibitor of SARS-CoV-2 exhibiting low cytotoxicity, characterized by an IC50 of 0.3 μM, effectuated through direct interact...
T79613 MPI60 98%
MPI60
MPI60 is a potent inhibitor of SARS-CoV-2 main protease (M^pro) exhibiting high antiviral efficacy, low cellular cytotoxicity, and considerable in vitro metaboli...
T79660 SARS-CoV-2 3CLpro-IN-17 98%
SARS-CoV-2 3CLpro-IN-17
Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].
T79661 SARS-CoV-2 3CLpro-IN-18 98%
SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 ...
T79663 E07 aptamer 98%
E07 aptamer
SARS-CoV-2 nsp14-IN-4 (Compound 12q) is a selective inhibitor of the SARS-CoV-2 nsp14 methyltransferase with an IC50 of 19 ± 2.5 nM. Lacking a zwitterionic chara...
T79836 Arbemnifosbuvir 1998705-63-7 98%
Arbemnifosbuvir
Arbemnifosbuvir, a drug interfering with the nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12), is utilized in...
T79866 Zevotrelvir 2773516-53-1 98%
Zevotrelvir
Zevotrelvir (Compound 52) serves as an inhibitor of coronavirus, demonstrating IC50 values below 0.1 μM for 229E hCoV protease and below 0.1 mM for SARS-CoV-3C-l...
T79884 D-4-77 98%
D-4-77
D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting an IC 50 of 0.95 μM, and possesses antiviral activity with an EC 50 of 0.49 μM. Furthermore, it suppr...
T79920 Debrisoquin 1131-64-2 98%
Debrisoquin
Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through TMPRSS2-dependent pathways, exhibiting an IC50...
T79947 10-Hydroxyaloin A 134863-91-5 98%
10-Hydroxyaloin A
Hydroxyaloin A (10-10-Hydroxyaloin A) is a potent inhibitor of SARS-CoV-2, demonstrating significant efficacy in binding to the active site of the SARS-CoV-2 mai...
T80010 (25S)-Antcin B 1312711-71-9 98%
(25S)-Antcin B
Antcin-B exhibits a high-affinity inhibition of 3CLPro, which is potentially significant in SARS-CoV-2 research [1].
T80575 Simaravibart 98%
Simaravibart
Simaravibart (MAD-0004J08), an IgG1κ monoclonal antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].
T80581 Plutavimab 2529854-88-2 98%
Plutavimab
Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2].
T80587 Alunacedase alfa 2416824-55-8 98%
Alunacedase alfa
Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell ent...
T80636 SARS-CoV-2-IN-59 850786-33-3 98%
SARS-CoV-2-IN-59
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It ex...
T81202 SARS-CoV-2-IN-69 78471-90-6 98%
SARS-CoV-2-IN-69
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-li...
T81203 SARS-CoV-2-IN-68 2682897-84-1 98%
SARS-CoV-2-IN-68
SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger domai...
T81204 SARS-CoV-2-IN-67 98%
SARS-CoV-2-IN-67
SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRS...
SARS-CoV-2 Mpro-IN-10
T79515
SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in res...
SARS-CoV-2 nsp14-IN-4
T79526
SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 ...
SARS-CoV-2-IN-55
T79570
SARS-CoV-2-IN-55 (compound 65) is an inhibitor of SARS-CoV-2 exhibiting low cytotoxicity, characterized by an IC50 of 0.3 μM, effectuated through direct interact...
MPI60
T79613
MPI60 is a potent inhibitor of SARS-CoV-2 main protease (M^pro) exhibiting high antiviral efficacy, low cellular cytotoxicity, and considerable in vitro metaboli...
SARS-CoV-2 3CLpro-IN-17
T79660
Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].
SARS-CoV-2 3CLpro-IN-18
T79661
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 ...
E07 aptamer
T79663
SARS-CoV-2 nsp14-IN-4 (Compound 12q) is a selective inhibitor of the SARS-CoV-2 nsp14 methyltransferase with an IC50 of 19 ± 2.5 nM. Lacking a zwitterionic chara...
Arbemnifosbuvir
T79836
Arbemnifosbuvir, a drug interfering with the nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12), is utilized in...
Zevotrelvir
T79866
Zevotrelvir (Compound 52) serves as an inhibitor of coronavirus, demonstrating IC50 values below 0.1 μM for 229E hCoV protease and below 0.1 mM for SARS-CoV-3C-l...
D-4-77
T79884
D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting an IC 50 of 0.95 μM, and possesses antiviral activity with an EC 50 of 0.49 μM. Furthermore, it suppr...
Debrisoquin
T79920
Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through TMPRSS2-dependent pathways, exhibiting an IC50...
10-Hydroxyaloin A
T79947
Hydroxyaloin A (10-10-Hydroxyaloin A) is a potent inhibitor of SARS-CoV-2, demonstrating significant efficacy in binding to the active site of the SARS-CoV-2 mai...
(25S)-Antcin B
T80010
Antcin-B exhibits a high-affinity inhibition of 3CLPro, which is potentially significant in SARS-CoV-2 research [1].
Simaravibart
T80575
Simaravibart (MAD-0004J08), an IgG1κ monoclonal antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].
Plutavimab
T80581
Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2].
Alunacedase alfa
T80587
Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell ent...
SARS-CoV-2-IN-59
T80636
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It ex...
SARS-CoV-2-IN-69
T81202
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-li...
SARS-CoV-2-IN-68
T81203
SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger domai...
SARS-CoV-2-IN-67
T81204
SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRS...
1 2 3 4 5 6 7 8 9
TargetMol