Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
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T79515 | SARS-CoV-2 Mpro-IN-10 | 98% |
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SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, exhibiting IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is utilized in res... | ||||
T79526 | SARS-CoV-2 nsp14-IN-4 | 98% |
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SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 ... | ||||
T79570 | SARS-CoV-2-IN-55 | 98% |
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SARS-CoV-2-IN-55 (compound 65) is an inhibitor of SARS-CoV-2 exhibiting low cytotoxicity, characterized by an IC50 of 0.3 μM, effectuated through direct interact... | ||||
T79613 | MPI60 | 98% |
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MPI60 is a potent inhibitor of SARS-CoV-2 main protease (M^pro) exhibiting high antiviral efficacy, low cellular cytotoxicity, and considerable in vitro metaboli... | ||||
T79660 | SARS-CoV-2 3CLpro-IN-17 | 98% |
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Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1]. | ||||
T79661 | SARS-CoV-2 3CLpro-IN-18 | 98% |
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SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 ... | ||||
T79663 | E07 aptamer | 98% |
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SARS-CoV-2 nsp14-IN-4 (Compound 12q) is a selective inhibitor of the SARS-CoV-2 nsp14 methyltransferase with an IC50 of 19 ± 2.5 nM. Lacking a zwitterionic chara... | ||||
T79836 | Arbemnifosbuvir | 1998705-63-7 | 98% |
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Arbemnifosbuvir, a drug interfering with the nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12), is utilized in... | ||||
T79866 | Zevotrelvir | 2773516-53-1 | 98% |
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Zevotrelvir (Compound 52) serves as an inhibitor of coronavirus, demonstrating IC50 values below 0.1 μM for 229E hCoV protease and below 0.1 mM for SARS-CoV-3C-l... | ||||
T79884 | D-4-77 | 98% |
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D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro, exhibiting an IC 50 of 0.95 μM, and possesses antiviral activity with an EC 50 of 0.49 μM. Furthermore, it suppr... | ||||
T79920 | Debrisoquin | 1131-64-2 | 98% |
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Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through TMPRSS2-dependent pathways, exhibiting an IC50... | ||||
T79947 | 10-Hydroxyaloin A | 134863-91-5 | 98% |
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Hydroxyaloin A (10-10-Hydroxyaloin A) is a potent inhibitor of SARS-CoV-2, demonstrating significant efficacy in binding to the active site of the SARS-CoV-2 mai... | ||||
T80010 | (25S)-Antcin B | 1312711-71-9 | 98% |
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Antcin-B exhibits a high-affinity inhibition of 3CLPro, which is potentially significant in SARS-CoV-2 research [1]. | ||||
T80575 | Simaravibart | 98% |
Simaravibart
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Simaravibart (MAD-0004J08), an IgG1κ monoclonal antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1]. | ||||
T80581 | Plutavimab | 2529854-88-2 | 98% |
Plutavimab
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Plutavimab is a humanized IgG1-κ monoclonal antibody targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) glycoprotein [1] [2]. | ||||
T80587 | Alunacedase alfa | 2416824-55-8 | 98% |
Alunacedase alfa
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Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell ent... | ||||
T80636 | SARS-CoV-2-IN-59 | 850786-33-3 | 98% |
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SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule that inhibits SARS-CoV-2 by targeting its main protease (Mpro). It ex... | ||||
T81202 | SARS-CoV-2-IN-69 | 78471-90-6 | 98% |
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SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-li... | ||||
T81203 | SARS-CoV-2-IN-68 | 2682897-84-1 | 98% |
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SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger domai... | ||||
T81204 | SARS-CoV-2-IN-67 | 98% |
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SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRS... |