T4371 |
CD437
|
125316-60-1
|
99.63%
|
|
CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.
|
T1611 |
Isotretinoin
|
4759-48-2
|
99.61%
|
|
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cel...
|
T1051 |
Retinoic acid
|
302-79-4
|
99.52%
|
|
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid in...
|
T3955 |
AR7
|
80306-38-3
|
99.52%
|
|
AR7 is a retinoic acid receptor α (RARα) antagonist.
|
T22767 |
ER 50891
|
187400-85-7
|
99.49%
|
|
ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast d...
|
T22843 |
HX 531
|
188844-34-0
|
99.43%
|
|
RXR antagonist
|
TN6735 |
Bigelovin
|
3668-14-2
|
99.4%
|
|
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pat...
|
T11847L |
Liarozole
|
115575-11-6
|
99.38%
|
|
Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of ar...
|
T68104 |
Mofarotene
|
125533-88-2
|
99.36%
|
|
Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tu...
|
TP1313L |
Cecropin B acetate
|
|
99.27%
|
|
Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA se...
|
T11303 |
Fluorobexarotene
|
1190848-23-7
|
99.23%
|
|
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene is a potent retinoid-X-receptor (RXR) agonist,...
|
T61588 |
AGN 192870
|
166977-57-7
|
99.22%
|
|
AGN 192870 is a potent retinoic acid receptor (RAR) antagonist.AGN 192870 can be used to study cell growth arrest, differentiation and apoptosis.
|
T77499 |
MSU-42011
|
2456434-36-7
|
99.04%
|
|
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist.MSU-42011 potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and...
|
T14946 |
Ch55
|
110368-33-7
|
99.01%
|
|
Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β recept...
|
T26854 |
BMS641
|
369364-50-1
|
98.98%
|
|
BMS641 (BMS-209641) is a selective and potent RARβ agonist.BMS641 has a high affinity for RARβ and synergistically activates RARβ and RARgamma to induce cellular...
|
T5341 |
WYC-209
|
2131803-90-0
|
98.91%
|
|
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
|
T1288 |
TTNPB
|
71441-28-6
|
98.84%
|
|
TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respective...
|
TQ0097 |
AGN 193109
|
171746-21-7
|
98.81%
|
|
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
|
T23005 |
MM 11253
|
345952-44-5
|
98.62%
|
|
MM 11253 is a RARγ antagonist with IC50 of 44nM.
|
T15811 |
LY2955303
|
1433497-19-8
|
98.56%
|
|
LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).
|