Ras

Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.

Cat. No.	Product name	CAS No.	Purity
T7764	CCG-222740	1922098-69-8	98.79%
T7764	CCG-222740 is an inhibitor of Rho/MRTF pathway
T9972	Divarasib	2417987-45-0	98.79%
T9972	Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly ...
T5469	K-Ras-IN-1	84783-01-7	98.72%
T5469	K-Ras-IN-1 is a K-Ras inhibitor.
T9407	Rasarfin	674359-73-0	98.58%
T9407	Rasarfin inhibits Ras and ARF6.
T22258	(S)-AMG-510	2252403-56-6	98.57%
T22258	(S)-AMG-510 is an S-type compound of AMG-510, a potent covalent inhibitor of KRAS G12C with potential antitumor activity.
T5379	(Rac)-Antineoplaston A10	77658-84-5	98.47%
T5379	(Rac)-Antineoplaston A10 (Antineoplaston A10) is a naturally occurring substance and the first antineoplaston in the human body to be chemically identified. It d...
T2267	BQU57	1637739-82-2	98.36%
T2267	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
T40286	KRAS G12C inhibitor 19	2649788-46-3	98.31%
T40286	KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in cellular assays, and the family inhibits tumor growth.
T3553	Y16	429653-73-6	98.26%
T3553	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
T2700	FTI-277 hydrochloride	180977-34-8	98.19%
T2700	FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
T8473	MLS000532223	16616-39-0	98.11%
T8473	MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
T16021	MBQ-167	2097938-73-1	98.07%
T16021	MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively).
T7609	ARS-1620	1698055-85-4	98%
T7609	ARS-1620 is a covalent inhibitor of K-RASG12C.
T1876	Kobe0065	436133-68-5	98%
T1876	Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; shows potent activity to competitively inhibit the binding of H...
T7131	Antineoplaston A10	91531-30-5	98%
T7131	Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.
T22249	1588-A4	1698027-20-1	98%
T22249	1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.
T6302	Lonafarnib	193275-84-2	98%
T6302	Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
T7326	6H05 (TFA)	2061344-88-3	98%
T7326	6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.
T7558	CID-1067700	314042-01-8	98%
T7558	CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).
T5597	ZT-12-037-01	2328073-61-4	98%
T5597	Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).