Home Tools
Log in
Cart

Ras

Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T9184 Compound 3344 2368246-78-8 98%
Compound 3344
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
T2014 CCG-1423 285986-88-1 99.98%
CCG-1423
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
T8870 1-(4-methansulfinylphenyl)ethanone 32361-73-2 99.95%
1-(4-methansulfinylphenyl)ethanone
The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.
T8756 KRAS inhibitor-9 300809-71-6 99.94%
KRAS inhibitor-9
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9...
T30778 CCG-257081 1922098-90-5 99.92%
CCG-257081
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MR...
T9184L Compound 3344 hydrochloride T9184L 99.89%
Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
T22062 CCG-100602 1207113-88-9 99.86%
CCG-100602
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
T3971 CASIN 425399-05-9 99.86%
CASIN
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
T6634 RBC8 361185-42-4 99.81%
RBC8
RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
T2463 ML141 71203-35-5 99.77%
ML141
ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
T15485 HJC0197 1383539-73-8 99.76%
HJC0197
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9...
T8006 Oncrasin-1 75629-57-1 99.68%
Oncrasin-1
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations
T22106 MLS-573151 10179-57-4 99.64%
MLS-573151
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 ...
T8930 CID44216842 1222513-26-9 99.63%
CID44216842
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM...
T0679 Ketoconazole 65277-42-1 99.62%
Ketoconazole
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
TN1413 Atranorin 479-20-9 99.57%
Atranorin
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent ...
T4619 ML-098 878978-76-8 99.52%
ML-098
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
T22991 ML-099 496775-95-2 99.48%
ML-099
pan activator of Ras-related GTPases
T6555 K-Ras(G12C) inhibitor 12 1469337-95-8 99.44%
K-Ras(G12C) inhibitor 12
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T72062 BI-2865 2937327-93-8 99.39%
BI-2865
BI-2865 is a non-covalent pan-KRAS inhibitor.BI-2865 binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with KD values of 6.9, 4.5, 32, 26, and 4.3 nM, respect...
Compound 3344
T9184
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
CCG-1423
T2014
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
1-(4-methansulfinylphenyl)ethanone
T8870
The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.
KRAS inhibitor-9
T8756
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9...
CCG-257081
T30778
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MR...
Compound 3344 hydrochloride
T9184L
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
CCG-100602
T22062
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
CASIN
T3971
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
RBC8
T6634
RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
ML141
T2463
ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
HJC0197
T15485
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9...
Oncrasin-1
T8006
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations
MLS-573151
T22106
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 ...
CID44216842
T8930
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM...
Ketoconazole
T0679
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Atranorin
TN1413
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent ...
ML-098
T4619
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
ML-099
T22991
pan activator of Ras-related GTPases
K-Ras(G12C) inhibitor 12
T6555
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
BI-2865
T72062
BI-2865 is a non-covalent pan-KRAS inhibitor.BI-2865 binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with KD values of 6.9, 4.5, 32, 26, and 4.3 nM, respect...
1 2 3 4 5 6
TargetMol