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ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN1654 Futoquinol 28178-92-9 98%
Futoquinol
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
TN3208 7,3',4'-Trihydroxy-3-benzyl-2H-chromene 1111897-60-9 98%
7,3',4'-Trihydroxy-3-benzyl-2H-chromene
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is a potential xanthine oxidase inhibitor.
TN4166 Griffipavixanthone 219649-95-3 98%
Griffipavixanthone
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mito...
TN3719 Cristacarpin 74515-47-2 98%
Cristacarpin
Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-l...
TN2501 1,5,6-Trihydroxy-3-methoxyxanthone 50868-52-5 98%
1,5,6-Trihydroxy-3-methoxyxanthone
1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
TN4094 Gallocatechin gallate 5127-64-0 98%
Gallocatechin gallate
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
TN5050 Sprengerinin C 88861-91-0 98%
Sprengerinin C
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
T13351 WY-135 2163060-83-9 98%
WY-135
WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively).
T13538 AlbA-DCA T13538 98%
AlbA-DCA
AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid subunit. It can induce a marked increase in intracellular ROS and ...
TN3741 Cyclocurcumin 153127-42-5 98%
Cyclocurcumin
Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rh...
TN4435 Licopyranocoumarin 117038-80-9 98%
Licopyranocoumarin
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane...
TN4286 Isodunnianol 139726-30-0 98%
Isodunnianol
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0...
TN7240 Erinacine A 156101-08-5 98%
Erinacine A
Erinacine A is an anticancer compound that can be extracted from the monkey head mushroom and is capable of inducing cancer cell death through the production of ...
TN1104 Cyanidin 3-sambubioside chloride 33012-73-6 98%
Cyanidin 3-sambubioside chloride
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active s...
TN1598 Dunnianol 139726-29-7 98%
Dunnianol
Dunnianol shows anti-inflammatory activity and moderate antibacterial activity.
TN4604 Myricanone 32492-74-3 98%
Myricanone
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
TN1952 Moracin P 102841-46-3 98%
Moracin P
Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tum...
TMA0424 Martynoside 67884-12-2 98%
Martynoside
Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynosi...
TN3753 Dalbergioidin 30368-42-4 98%
Dalbergioidin
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...
TN4872 Pyrroside B 116271-35-3 98%
Pyrroside B
Pyrroside B shows stronger antioxidative activity than that of α-tocopherol.
Futoquinol
TN1654
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
7,3',4'-Trihydroxy-3-benzyl-2H-chromene
TN3208
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is a potential xanthine oxidase inhibitor.
Griffipavixanthone
TN4166
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mito...
Cristacarpin
TN3719
Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-l...
1,5,6-Trihydroxy-3-methoxyxanthone
TN2501
1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
Gallocatechin gallate
TN4094
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
Sprengerinin C
TN5050
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
WY-135
T13351
WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively).
AlbA-DCA
T13538
AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid subunit. It can induce a marked increase in intracellular ROS and ...
Cyclocurcumin
TN3741
Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rh...
Licopyranocoumarin
TN4435
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane...
Isodunnianol
TN4286
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0...
Erinacine A
TN7240
Erinacine A is an anticancer compound that can be extracted from the monkey head mushroom and is capable of inducing cancer cell death through the production of ...
Cyanidin 3-sambubioside chloride
TN1104
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active s...
Dunnianol
TN1598
Dunnianol shows anti-inflammatory activity and moderate antibacterial activity.
Myricanone
TN4604
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
Moracin P
TN1952
Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tum...
Martynoside
TMA0424
Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynosi...
Dalbergioidin
TN3753
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...
Pyrroside B
TN4872
Pyrroside B shows stronger antioxidative activity than that of α-tocopherol.
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TargetMol