T78205 |
ROCK2-IN-6 hydrochloride
|
2762238-94-6
|
98%
|
|
ROCK2-IN-6 hydrochloride (Comp A) serves as a selective inhibitor of ROCK2, applicable for research into ROCK-mediated diseases, autoimmune disorders, and inflam...
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T79077 |
ROCK-IN-6
|
2489328-74-5
|
98%
|
|
ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1]....
|
T79080 |
ROCK-IN-7
|
2376635-95-7
|
98%
|
|
ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].
|
T79809 |
ROCK-IN-8
|
1621103-79-4
|
98%
|
|
ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research, demonstrat...
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T79832 |
ROCK2-IN-6
|
2260506-59-8
|
98%
|
|
ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].
|
T79833 |
ROCK-IN-9
|
2643334-76-1
|
98%
|
|
ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM. It demonstrates favorable pharmacokinetic properties i...
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T79905 |
Akt/ROCK-IN-1
|
|
98%
|
|
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively. It possesses antitumor efficacy aga...
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T81261 |
ROCK2-IN-7
|
3000541-95-4
|
98%
|
|
ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis. It exhibits its efficacy in targeting ROCK2 enzymes within HaCaT ...
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T82766 |
CCG-232964
|
2349373-70-0
|
98%
|
|
CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].
|
T7492 |
Ripasudil free base
|
223645-67-8
|
98%
|
|
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.
|
T13364 |
YAP/TAZ inhibitor-1
|
2093565-23-0
|
98%
|
|
YAP/TAZ inhibitor-1 is an inhibitor of YAP/TAZ (IC50 of <0.100 μΜ in firefly luciferase assay).
|
T13972 |
Y-9738
|
59399-41-6
|
98%
|
|
Y-9738 is an agent of hypolipidemic.
|
T16855 |
SB-772077B dihydrochloride
|
607373-46-6
|
98%
|
|
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).
|
TN1533 |
Cucurbitacin A
|
6040-19-3
|
98%
|
|
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/RO...
|
TN1985 |
Neoprzewaquinone A
|
630057-39-5
|
98%
|
|
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 ...
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T15808 |
Merestinib dihydrochloride
|
1206801-37-7
|
98%
|
|
Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against M...
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T15798 |
LX7101
|
1192189-69-7
|
98%
|
|
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
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T7552 |
H-1152
|
451462-58-1
|
98%
|
|
H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).
|
T10358 |
Netarsudil Dihydrochloride
|
1253952-02-1
|
99.98%
|
|
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective...
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TQ0187 |
SR-3677
|
1072959-67-1
|
99.91%
|
|
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
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