T12628 |
(R)-MG-132
|
1211877-36-9
|
98.45%
|
|
(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.
|
T3786 |
Tomatine
|
17406-45-0
|
98.42%
|
|
Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.
|
T8397 |
Ixazomib citrate
|
1239908-20-3
|
98.37%
|
|
Ixazomib citrate (MLN9708) is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (IC50 of 3.4 nM ) with ...
|
T10061 |
(1S,2S)-Bortezomib
|
1132709-14-8
|
98.33%
|
|
(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S ...
|
T14005 |
1G244
|
847928-32-9
|
98.23%
|
|
1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 values of 14 and 53 nM against DPP8 and DPP9, and The Ki ...
|
T39214L |
LXE408 fumarate
|
|
98.10%
|
|
LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani pro...
|
T2122 |
Ixazomib
|
1072833-77-2
|
98.07%
|
|
Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S pro...
|
T2016 |
MLN9708
|
1201902-80-8
|
98%
|
|
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 (Ixazom...
|
T6583 |
MG-101
|
110044-82-1
|
98%
|
|
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
|
T1502 |
Vildagliptin
|
274901-16-5
|
98%
|
|
Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cy...
|
TN1262 |
3-Feruloylquinic acid
|
1899-29-2
|
97.83%
|
|
3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
|
T13858 |
RA190
|
1617495-03-0
|
97.69%
|
|
RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
|
T7854 |
Bortezomib-pinanediol
|
205393-22-2
|
97.5%
|
|
Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.
|
T16169 |
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride
|
4272-74-6
|
97.44%
|
|
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-a...
|
T67852 |
Linagliptin Methyldimer
|
1418133-47-7
|
97.23%
|
|
Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
|
T21617 |
MG-115
|
133407-86-0
|
97.12%
|
|
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifi...
|
T8350 |
TPCK
|
402-71-1
|
96.77%
|
|
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
|
T2154 |
MG-132
|
133407-82-6
|
95.91%
|
|
MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induc...
|
T12079 |
ML604440
|
1140517-08-3
|
95.24%
|
|
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
|
T6999 |
Teneligliptin hydrobromide
|
906093-29-6
|
100%
|
|
Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, r...
|