T16568 |
PR-924
|
1416709-79-9
|
98%
|
|
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple...
|
T78625 |
Z-Ala-Arg-Arg-AMC
|
90468-18-1
|
98%
|
|
Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) serves as a fluorogenic substrate designed to assay the trypsin-like activity within the proteasome [1].
|
T78632 |
Z-LLY-FMK
|
133410-84-1
|
98%
|
|
Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems. Specifically, this...
|
T78640 |
Z-LLF-CHO
|
133429-58-0
|
98%
|
|
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM. A...
|
T79316 |
Antitrypanosomal agent 15
|
|
98%
|
|
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4 ...
|
T79842 |
Davelizomib
|
2409841-51-4
|
98%
|
|
Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].
|
T80101 |
Z-GGF-CMK
|
35172-59-9
|
98%
|
|
Z-GGF-CMK, a protease inhibitor, impedes ClpP1P2 and proteasome activity and demonstrates cytotoxic effects on HepG2 cells, with a CC50 value of 125 μM [1].
|
T80102 |
Z-Leu-Leu-Tyr-COCHO
|
204649-66-1
|
98%
|
|
Z-Leu-Leu-Tyr-COCHO is a potent inhibitor of chymotrypsin-like activity, exhibiting a Ki value of 3.0 nM [1].
|
T80129 |
Baceridin
|
1622872-91-6
|
98%
|
|
Baceridin, a cyclic hexapeptide and proteasome inhibitor, can be isolated from the culture medium of Epiphytic Bacillus. It has the ability to impede cell cycle ...
|
T80241 |
Calpastatin subdomain B
|
128578-18-7
|
98%
|
|
Calpastatin subdomain B is a bioactive peptide that inhibits calpain activity.
|
T80697 |
β5i-IN-1
|
|
98%
|
|
β5i-IN-1 is a selective inhibitor of β5i, exhibiting potent activity with an IC50 of 8.463 nM. It modulates immune responses by promoting the release of TNF-α an...
|
T80735 |
Z-Gly-Pro-Phe-Leu-CHO
|
159659-05-9
|
98%
|
|
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) of ...
|
T81371 |
Proteasome-IN-5
|
1613134-34-1
|
98%
|
|
Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].
|
T81373 |
Proteasome β2c/i-IN-1
|
2322333-75-3
|
98%
|
|
Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].
|
T81909 |
LU-002i
|
1838705-22-8
|
98%
|
|
LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].
|
T12561 |
Proteasome-IN-1
|
374080-21-4
|
98%
|
|
Proteasome-IN-1 is an inhibitor of proteasome.
|
T15702 |
Lactacystin
|
133343-34-7
|
98%
|
|
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacyst...
|
T10238 |
Aclacinomycin A hydrochloride
|
75443-99-1
|
98%
|
|
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (c...
|
T11924 |
M3258
|
2285330-15-4
|
98%
|
|
LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer, is an inhibitor of imm...
|
T15678 |
KZR-504
|
1629052-78-3
|
98%
|
|
KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
|