T27630 |
Isbogrel
|
89667-40-3
|
97.06%
|
|
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks...
|
T10960L |
Darbufelone mesylate
|
139340-56-0
|
96.81%
|
|
Darbufelone mesylate (CI-1004 mesylate) inhibited PGF2α and LTB4 in cells. Darbufelone mesylate inhibited PGHS-2 with IC50 value of 0.19 μM and PGHS-1 with IC50 ...
|
T27084 |
Crisdesalazine
|
927685-43-6
|
95.95%
|
|
Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1). Crisdesalazine reduces autophagosome formation, axonopathy, and mo...
|
T0795 |
Rutin
|
153-18-4
|
95%
|
|
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarci...
|
T13563 |
AZ-1355
|
75451-07-9
|
100%
|
|
AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.
|
T77699 |
EP4-IN-1
|
2455480-28-9
|
100%
|
|
EP4-IN-1 is a potent prostaglandin EP4 receptor inhibitor with potential anti-tumor, anti-inflammatory and analgesic activities for the study of immune and tumor...
|
T2428 |
TG6-10-1
|
1415716-58-3
|
100%
|
|
TG6-10-1 is an EP2 antagonist.
|
T5841 |
Travoprost
|
157283-68-6
|
100%
|
|
Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.
|
T36619 |
Aligeron
|
70713-45-0
|
100%
|
|
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit P...
|
T2538 |
Bimatoprost
|
155206-00-1
|
100%
|
|
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertensio...
|
T6236 |
Ozagrel
|
82571-53-7
|
100%
|
|
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative...
|
T3915 |
Ginsenoside Ro
|
34367-04-9
|
|
|
Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with ...
|
T1338 |
Sucralfate
|
54182-58-0
|
|
|
Sucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active ...
|
T7359 |
CAY10471 Racemate
|
844639-57-2
|
|
|
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP re...
|
T4635 |
Ralinepag
|
1187856-49-0
|
98%
|
|
Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and r...
|
TN1257 |
3-O-Acetyl-α-boswellic acid
|
89913-60-0
|
98%
|
|
3-O-Acetyl-α-boswellic acid (α-Boswellic acid acetate) has strong anti-inflammatory activity.
|
T5505 |
Terutroban
|
165538-40-9
|
98%
|
|
Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis.
|
T23331 |
SC 51089
|
146033-02-5
|
98%
|
|
SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and anti-injury activity that ameliorates mot...
|
T22285 |
Carboprost
|
35700-23-3
|
98%
|
|
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to re...
|
T17232 |
Vidupiprant
|
1169483-24-2
|
98%
|
|
Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in...
|