Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.

Cat. No.	Product name	CAS No.	Purity
T3520	Setipiprant	866460-33-5	99.16%
T3520	Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 ...
TQ0203	Tafluprost	209860-87-7	99.16%
TQ0203	Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.
T1562	Rebamipide	90098-04-7	99.15%
T1562	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which re...
T5482	TG4-155	1164462-05-8	99.14%
T5482	TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels...
TQ0025	E7046	1369489-71-3	99.09%
TQ0025	E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting anti-tumor activities.
T12268	NTP42	2055599-51-2	99.09%
T12268	NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
T1626	Prostaglandin E1	745-65-3	99.05%
T1626	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent...
T2S0765	Epibetulinic acid	38736-77-5	99.02%
T2S0765	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) ...
T3868	Agnuside	11027-63-7	98.98%
T3868	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, ...
T8883	Pizuglanstat	1244967-98-3	98.96%
T8883	Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.
TN1134	Euscaphic acid	53155-25-2	98.93%
TN1134	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 w...
T3903	Angoroside C	115909-22-3	98.92%
T3903	Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidativ...
T67958	Pirmagrel	85691-74-3	98.83%
T67958	pirmagrel is a potent thromboxane synthase inhibitor.
TN3669	Cis-N-Feruloyltyramine	80510-09-4	98.75%
TN3669	Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyram...
T23861	CAY10526	938069-71-7	98.75%
T23861	CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
T2786	Oxysophocarpine	26904-64-3	98.73%
T2786	Oxysophocarpine is extracted from Sophra flavescens Ait.
T5774	Demethylsuberosin	21422-04-8	98.65%
T5774	7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory ...
T62061	COX-2-IN-6	2756347-91-6	98.62%
T62061	COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 μM and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-dr...
T10031	EP1-antagonist-1	851204-35-8	98.51%
T10031	EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
T3276	Benorilate	5003-48-5	98.39%
T3276	Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.