T15690 |
L-902688
|
634193-54-7
|
98%
|
|
L-902688 is an orally active EP4 receptor agonist (Ki: 0.38 nM; EC50: 0.6 nM). L-902688 displays >4,000-fold selective for EP4 over other EP and prostanoid recep...
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
T77630 |
EP3 antagonist 4
|
2408297-80-1
|
98%
|
|
EP3 antagonist 4 is an EP3 antagonist that inhibits hEP with a Ki of 2 nM. EP3 antagonist 4 showed low in vivo clearance, high oral AUC and good bioavailability ...
|
TN3839 |
Desoxo-narchinol A
|
53859-06-6
|
98%
|
|
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity agains...
|
TN3144 |
6,4'-Dihydroxy-7-methoxyflavanone
|
189689-32-5
|
98%
|
|
6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) with antioxidant, an...
|
T16988 |
Taprenepag isopropyl
|
1005549-94-9
|
98%
|
|
Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
T10046 |
16,16-Dimethyl prostaglandin E2
|
39746-25-3
|
98%
|
|
16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an int...
|
TN5019 |
Siegeskaurolic acid
|
52645-97-3
|
98%
|
|
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via...
|
T11340 |
Furprofen
|
66318-17-0
|
98%
|
|
Furprofen, a non-steroidal anti-inflammatory drug (NSAID), exerts its effects by inhibiting the synthesis of prostaglandin (PGE). This compound demonstrates anal...
|
TN4879 |
Questinol
|
35688-09-6
|
98%
|
|
Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit th...
|
T15689 |
L-798106
|
244101-02-8
|
98%
|
|
L-798106 is a highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM). It also has micromolar activities at EP4, EP1, and EP2 receptors (Ki: 916 nM, >500...
|
TN4194 |
Heliangin
|
13323-48-3
|
98%
|
|
Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells...
|
T16389 |
Omidenepag
|
1187451-41-7
|
98%
|
|
Omidenepag is a pharmacologically active form of Omidenepag Isopropyl and is a selective, non-prostanoid EP2 receptor agonist (EC50: 1.1 nM). Omidenepag displays...
|
TN1874 |
Liriodendrin
|
573-44-4
|
98%
|
|
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has an...
|
TN4162 |
Goshonoside F5
|
90851-28-8
|
98%
|
|
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
|
T16504 |
PF-4693627
|
1312815-93-2
|
98%
|
|
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by oste...
|
T38635 |
Kdo2-Lipid A ammonium
|
1246298-62-3
|
98%
|
|
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
|
TMA0291 |
Dehydroglyasperin D
|
517885-72-2
|
98%
|
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
|
TN4046 |
Excisanin A
|
78536-37-5
|
98%
|
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
|