Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product name	CAS No.	Purity
T24799	SKA-111	1369170-24-0	99.79%
T24799	SKA-111 is a selective calcium-activated potassium phannel (potassium phannel ) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial c...
T0344	Miconazole	22916-47-8	99.78%
T0344	Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.
T1674	Nateglinide	105816-04-4	99.78%
T1674	Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy ...
T1634	Glibenclamide	10238-21-8	99.77%
T1634	Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T1049L	Oxybutynin	5633-20-5	99.77%
T1049L	Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.
T10979	DCPIB	82749-70-0	99.76%
T10979	DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM,...
T17243	VU0463271	1391737-01-1	99.75%
T17243	VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potass...
T0150	Hydroxyhexamide	3168-01-2	99.75%
T0150	Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.
T0700	Ursodeoxycholic acid	128-13-2	99.74%
T0700	Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T0249	N-Acetylprocainamide	32795-44-1	99.74%
T0249	N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic dr...
T4030	ML213	489402-47-3	99.74%
T4030	ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respect...
T4224	ML335	825658-06-8	99.73%
T4224	ML335 is a selective activator of TREK-1 and TREK-2.
T7899	VU0810464	2126040-21-7	99.73%
T7899	VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
T3557	GAL-021	1380341-99-0	99.73%
T3557	GAL-021 an intravenous BKCa-channel blocker.
T20968	CyPPA	73029-73-9	99.72%
T20968	CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
TQ0139	VU 0240551	893990-34-6	99.72%
TQ0139	VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
T1650	Chlorzoxazone	95-25-0	99.72%
T1650	Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.
T0858	Flufenamic acid	530-78-9	99.71%
T0858	Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
T3S0081	Oxypeucedanin	737-52-0	99.71%
T3S0081	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU1...
T9778	KCNQ1 activator-1	1008671-38-2	99.71%
T9778	2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- is a potent KCNQ1 channel activator that can be used in long QT syndrome (LQTS) ...