T4316 |
ML365
|
947914-18-3
|
99.91%
|
|
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
|
T72066 |
CHET3
|
2489231-47-0
|
99.91%
|
|
CHET3 is a TASK-3 inhibitor that can be used to study pain.
|
T1073 |
Dronedarone hydrochloride
|
141625-93-6
|
99.91%
|
|
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
|
T22826 |
GW 542573X
|
660846-41-3
|
99.91%
|
|
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of...
|
T3876 |
Loureirin B
|
119425-90-0
|
99.91%
|
|
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress...
|
TQ0150 |
Levcromakalim
|
94535-50-9
|
99.91%
|
|
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.
|
T3054 |
Daurisoline
|
70553-76-3
|
99.90%
|
|
Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.
|
T13320L |
VU591
|
1222810-74-3
|
99.9%
|
|
1222810-74-3
|
T10977 |
DCEBIO
|
60563-36-2
|
99.89%
|
|
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of...
|
T1050 |
Prazosin hydrochloride
|
19237-84-4
|
99.87%
|
|
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism n...
|
T27753 |
KT-362 fumarate
|
105394-80-7
|
99.87%
|
|
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
|
T29050 |
UK 66914
|
113049-11-9
|
99.86%
|
|
UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.
|
TN1092 |
O-Nornuciferine
|
3153-55-7
|
99.86%
|
|
O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
|
T8182 |
Guanfu base A
|
1394-48-5
|
99.85%
|
|
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
|
T2170 |
SKF-96365 hydrochloride
|
130495-35-1
|
99.85%
|
|
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells...
|
T12256 |
NS8593 hydrochloride
|
875755-24-1
|
99.83%
|
|
NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .
|
T2280 |
Endoxifen (Z-isomer)
|
112093-28-4
|
99.81%
|
|
Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase ac...
|
T6592 |
ML133 hydrochloride
|
1222781-70-5
|
99.81%
|
|
ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 a...
|
T1676 |
Rosuvastatin
|
287714-41-4
|
99.8%
|
|
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the...
|
TNU0864 |
HUP30
|
312747-21-0
|
99.8%
|
|
HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.
|