TN1874 |
Liriodendrin
|
573-44-4
|
98%
|
|
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has an...
|
T12865 |
SCH-23390 maleate
|
87134-87-0
|
98%
|
|
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
|
TN5060 |
Stauntosaponin A
|
1417887-91-2
|
98%
|
|
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
|
TN4638 |
Neolinine
|
112515-37-4
|
98%
|
|
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
|
T0801 |
Tannic acid
|
1401-55-4
|
AR
|
|
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
|
T26324 |
VU0071063
|
333415-38-6
|
99.99%
|
|
VU0071063 is a Kir6.2/SUR1 activator.
|
T0127 |
Glimepiride
|
93479-97-1
|
99.97%
|
|
Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
|
T0451 |
Minoxidil
|
38304-91-5
|
99.97%
|
|
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
|
T3303 |
ML277
|
1401242-74-7
|
99.97%
|
|
ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
|
T3332 |
Isosteviol
|
27975-19-5
|
99.97%
|
|
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
|
T2088 |
APD668
|
832714-46-2
|
99.97%
|
|
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
|
T12478 |
Pinacidil monohydrate
|
85371-64-8
|
99.96%
|
|
Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
|
T13320 |
VU591 hydrochloride
|
1315380-70-1
|
99.95%
|
|
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of t...
|
T8135 |
Minoxidil sulfate
|
83701-22-8
|
99.93%
|
|
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
|
T15758 |
Linopirdine
|
105431-72-9
|
99.92%
|
|
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Lino...
|
T4316 |
ML365
|
947914-18-3
|
99.91%
|
|
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
|
T1073 |
Dronedarone hydrochloride
|
141625-93-6
|
99.91%
|
|
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
|
T22826 |
GW 542573X
|
660846-41-3
|
99.91%
|
|
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of...
|
T3876 |
Loureirin B
|
119425-90-0
|
99.91%
|
|
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress...
|
TQ0150 |
Levcromakalim
|
94535-50-9
|
99.91%
|
|
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.
|