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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN1874 Liriodendrin 573-44-4 98%
Liriodendrin
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has an...
T12865 SCH-23390 maleate 87134-87-0 98%
SCH-23390 maleate
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
TN5060 Stauntosaponin A 1417887-91-2 98%
Stauntosaponin A
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
TN4638 Neolinine 112515-37-4 98%
Neolinine
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
T0801 Tannic acid 1401-55-4 AR
Tannic acid
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
T26324 VU0071063 333415-38-6 99.99%
VU0071063
VU0071063 is a Kir6.2/SUR1 activator.
T0127 Glimepiride 93479-97-1 99.97%
Glimepiride
Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
T0451 Minoxidil 38304-91-5 99.97%
Minoxidil
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
T3303 ML277 1401242-74-7 99.97%
ML277
ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
T3332 Isosteviol 27975-19-5 99.97%
Isosteviol
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
T2088 APD668 832714-46-2 99.97%
APD668
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
T12478 Pinacidil monohydrate 85371-64-8 99.96%
Pinacidil monohydrate
Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
T13320 VU591 hydrochloride 1315380-70-1 99.95%
VU591 hydrochloride
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of t...
T8135 Minoxidil sulfate 83701-22-8 99.93%
Minoxidil sulfate
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
T15758 Linopirdine 105431-72-9 99.92%
Linopirdine
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Lino...
T4316 ML365 947914-18-3 99.91%
ML365
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
T1073 Dronedarone hydrochloride 141625-93-6 99.91%
Dronedarone hydrochloride
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T22826 GW 542573X 660846-41-3 99.91%
GW 542573X
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of...
T3876 Loureirin B 119425-90-0 99.91%
Loureirin B
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress...
TQ0150 Levcromakalim 94535-50-9 99.91%
Levcromakalim
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.
Liriodendrin
TN1874
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has an...
SCH-23390 maleate
T12865
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
Stauntosaponin A
TN5060
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
Neolinine
TN4638
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
Tannic acid
T0801
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
VU0071063
T26324
VU0071063 is a Kir6.2/SUR1 activator.
Glimepiride
T0127
Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
Minoxidil
T0451
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
ML277
T3303
ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
Isosteviol
T3332
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
APD668
T2088
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
Pinacidil monohydrate
T12478
Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
VU591 hydrochloride
T13320
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of t...
Minoxidil sulfate
T8135
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
Linopirdine
T15758
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Lino...
ML365
T4316
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
Dronedarone hydrochloride
T1073
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
GW 542573X
T22826
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of...
Loureirin B
T3876
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress...
Levcromakalim
TQ0150
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.
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TargetMol