Home Tools
Log in
Cart

Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T30544 BMS-919373 1272353-82-8 98.51%
BMS-919373
BMS-919373 is a potassium channel Kv1.5 (KCNA5) inhibitor for atrial fibrillation and acute coronary syndrome.
TN1757 Hypophyllanthin 33676-00-5 98.39%
Hypophyllanthin
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
T1054 Tolbutamide 64-77-7 98.37%
Tolbutamide
Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
T3192 NS1643 448895-37-2 98.37%
NS1643
NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.
T7653 JNJ 303 878489-28-2 98.33%
JNJ 303
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
T5336 Zacopride hydrochloride 101303-98-4 98.32%
Zacopride hydrochloride
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
T0161 Pantoprazole Sodium Hydrate 164579-32-2 98.32%
Pantoprazole Sodium Hydrate
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus c...
T9070 ASP2905 792184-90-8 98.29%
ASP2905
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychot...
T3102 NS-1619 153587-01-0 98.28%
NS-1619
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T30520 BMS-394136 343246-73-1 98.25%
BMS-394136
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
T14666 BL-1249 18200-13-0 98.25%
BL-1249
BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).
T1278 Astemizole 68844-77-9 98.24%
Astemizole
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 ...
T14984 CLP257 1181081-71-9 98.13%
CLP257
CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviate...
T12504 (+)-KCC2 blocker 1 1228439-71-1 98.12%
(+)-KCC2 blocker 1
(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).
T16347 NS3623 343630-41-1 98.1%
NS3623
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 act...
T16110 ML418 1928763-08-9 98.1%
ML418
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
T1527 Gliclazide 21187-98-4 98.08%
Gliclazide
Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the panc...
T23516 VU590 313505-85-0 98.06%
VU590
VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1).VU590 inhibits Kir7.1 and modulates uterine myometrial contr...
T8372 VU0134992 755002-90-5 98.03%
VU0134992
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM
T68730 AVE1231 767334-89-4 98.03%
AVE1231
AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.
BMS-919373
T30544
BMS-919373 is a potassium channel Kv1.5 (KCNA5) inhibitor for atrial fibrillation and acute coronary syndrome.
Hypophyllanthin
TN1757
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Tolbutamide
T1054
Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
NS1643
T3192
NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.
JNJ 303
T7653
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
Zacopride hydrochloride
T5336
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
Pantoprazole Sodium Hydrate
T0161
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus c...
ASP2905
T9070
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychot...
NS-1619
T3102
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
BMS-394136
T30520
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
BL-1249
T14666
BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).
Astemizole
T1278
Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 ...
CLP257
T14984
CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviate...
(+)-KCC2 blocker 1
T12504
(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).
NS3623
T16347
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 act...
ML418
T16110
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
Gliclazide
T1527
Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the panc...
VU590
T23516
VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1).VU590 inhibits Kir7.1 and modulates uterine myometrial contr...
VU0134992
T8372
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM
AVE1231
T68730
AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
TargetMol