T5585 |
AM-92016 hydrochloride
|
133229-11-5
|
99.02%
|
|
AM-92016 is a specific blocker of rectifier potassium current. AM-92016 delays rectifier potassium channel and repolarizes the membrane thereby restricting the d...
|
T6186 |
TRAM-34
|
289905-88-0
|
99.01%
|
|
TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not b...
|
T6504 |
Flupirtine maleate
|
75507-68-5
|
98.99%
|
|
Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a s...
|
T3402 |
20(S)-Ginsenoside Rg3
|
14197-60-5
|
98.99%
|
|
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhib...
|
T16444 |
PD-118057
|
313674-97-4
|
98.97%
|
|
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membran...
|
T17262 |
XE 991 dihydrochloride
|
122955-13-9
|
98.96%
|
|
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and...
|
T16109 |
ML402
|
298684-44-3
|
98.93%
|
|
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
|
T1334 |
Hydroquinidine
|
1435-55-8
|
98.9%
|
|
Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.
|
T26689 |
AVE-0118
|
498577-53-0
|
98.89%
|
|
AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.
|
T2996 |
Tetrandrine
|
518-34-3
|
98.88%
|
|
Tetrandrine (Sinomenine A) is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channe...
|
T28544 |
RL648_81
|
1919050-87-5
|
98.85%
|
|
RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.
|
T1510 |
Rosuvastatin calcium
|
147098-20-2
|
98.85%
|
|
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activit...
|
T8977 |
Kv2-IN-A1
|
689297-68-5
|
98.83%
|
|
Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.
|
T15555 |
IK1 inhibitor PA-6
|
500715-03-7
|
98.77%
|
|
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse K...
|
TMS2171 |
(±)-Naringenin
|
67604-48-2
|
98.73%
|
|
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes...
|
T1603 |
Glipizide
|
29094-61-9
|
98.66%
|
|
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
|
T1206 |
Amsacrine
|
51264-14-3
|
98.59%
|
|
Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. Amsacrine also expresses topoisomerase inhibitor activity, sp...
|
T32873 |
Maralixibat Chloride
|
228113-66-4
|
98.54%
|
|
Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
|
T0075 |
Nicorandil
|
65141-46-0
|
98.52%
|
|
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods...
|
T15385 |
Glibornuride
|
26944-48-9
|
98.51%
|
|
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.
|