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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Cat. No. Product name CAS No. Purity Chemical Structure
TNU0864 HUP30 312747-21-0 98%
HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.
T2434 LY 303511 154447-38-8 98%
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
TN2306 Wilfordine 37239-51-3 98%
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN4638 Neolinine 112515-37-4 98%
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
TN3042 4-Hydroxycinnamamide 194940-15-3 98%
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
TN3319 9-Hydroxycanthin-6-one 138544-91-9 98%
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
T32873 Maralixibat Chloride 228113-66-4 98%
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
TMA0805 Lupanine 550-90-3 98%
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
TN4322 Isopulegol 7786-67-6 98%
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
TMA0763 Methyl 3,4,5-trimethoxycinnamate 7560-49-8 98%
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
T14040 4-Hydroxytolbutamide 5719-85-7 98%
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
T67917 ML353 98%
ML353 is a selective activator of TREK-1 and TREK-2 and a selective ligand (Ki =18.2 nM) of the silence-allosteric regulator (SAM) of mGlu5. ML353 increased the ...
T11753 Keto Ziprasidone 884305-07-1 98%
Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist. Keto Ziprasidone is an impurity of Ziprasidone.
T14666 BL-1249 18200-13-0 98%
BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) tha...
TN3636 Chlorahololide C 1007859-25-7 98%
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
TN3460 Asebogenin 520-42-3 98%
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
TN3379 Allocryptopine 24240-04-8 98%
Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cyto...
T16285 Neosolaniol 36519-25-2 98%
Neosolaniol evokes a robust anorectic response. Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp.
TN1367 Alismol 87827-55-2 98%
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...
T6827 Endoxifen Z-isomer hydrochloride 1032008-74-4 98%
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
HUP30
TNU0864
HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.
LY 303511
T2434
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
Wilfordine
TN2306
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
Neolinine
TN4638
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
4-Hydroxycinnamamide
TN3042
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
9-Hydroxycanthin-6-one
TN3319
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
Maralixibat Chloride
T32873
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
Lupanine
TMA0805
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
Isopulegol
TN4322
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
Methyl 3,4,5-trimethoxycinnamate
TMA0763
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
4-Hydroxytolbutamide
T14040
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
ML353
T67917
ML353 is a selective activator of TREK-1 and TREK-2 and a selective ligand (Ki =18.2 nM) of the silence-allosteric regulator (SAM) of mGlu5. ML353 increased the ...
Keto Ziprasidone
T11753
Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist. Keto Ziprasidone is an impurity of Ziprasidone.
BL-1249
T14666
BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) tha...
Chlorahololide C
TN3636
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
Asebogenin
TN3460
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
Allocryptopine
TN3379
Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cyto...
Neosolaniol
T16285
Neosolaniol evokes a robust anorectic response. Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp.
Alismol
TN1367
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...
Endoxifen Z-isomer hydrochloride
T6827
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
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