T0188 |
Fluticasone (propionate)
|
80474-14-2
|
99.65%
|
|
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid recep...
|
T67749 |
Fuzapladib
|
141283-87-6
|
99.65%
|
|
Fuzapladib (IS-741) (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of...
|
T16108 |
ML349
|
890819-86-0
|
99.59%
|
|
ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).
|
T21907 |
PACOCF3
|
141022-99-3
|
99.57%
|
|
PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PA...
|
T10017 |
1-Linoleoyl Glycerol
|
2277-28-3
|
99.56%
|
|
1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl...
|
TCS1554 |
Trans-Benzylideneacetone
|
1896-62-4
|
99.55%
|
|
trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.
|
TN6993 |
Benzylideneacetone
|
122-57-6
|
99.52%
|
|
Benzylideneacetone, a monoterpene produced by the insect pathogenic bacterium Xenorhabdus nematophila, is a phospholipase A2 (PLA2) inhibitor with inhibitory eff...
|
T3439 |
ML348
|
899713-86-1
|
99.51%
|
|
ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).
|
T11874 |
Lp-PLA2-IN-3
|
2196245-16-4
|
99.49%
|
|
Lp-PLA2-IN-3 is a potent and orally bioactive lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor that inhibits recombinant human Lp-PLA2 with an IC50 va...
|
T14903 |
CCT129957
|
883098-58-6
|
99.44%
|
|
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inh...
|
T77638 |
BIRM 271
|
149106-77-4
|
99.38%
|
|
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and ...
|
T5454 |
N-(p-amylcinnamoyl) Anthranilic Acid
|
110683-10-8
|
99.35%
|
|
N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.
|
T0458 |
Indomethacin
|
53-86-1
|
99.27%
|
|
Indomethacin (Indometacin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor.
|
T15782 |
Lp-PLA2-IN-1
|
1420367-28-7
|
99.25%
|
|
Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) also inhibits to compositions ...
|
T3417 |
Amentoflavone
|
1617-53-4
|
99.22%
|
|
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for ...
|
T77594 |
VU534
|
923509-20-0
|
99.22%
|
|
VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related t...
|
TMO2790 |
1-Naphthaleneacetic acid
|
86-87-3
|
99.18%
|
|
1-Naphthaleneacetic acid (Transplantone) , is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingr...
|
T21777 |
VU0359595
|
1246303-14-9
|
99.15%
|
|
VU0359595 (ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1...
|
T3580 |
FIPI
|
939055-18-2
|
99.08%
|
|
FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PL...
|
T77616 |
VU533
|
923417-09-8
|
99.08%
|
|
VU533 (Nape-Pld activator) is a NAPE-PLD activator with an EC50 value of 0.30 µM.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533...
|