T8968 |
ML299
|
1426916-00-8
|
98%
|
|
ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).
|
TP1299 |
Melittin
|
20449-79-0
|
98%
|
|
Melittin, a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity...
|
T21681 |
AACOCF3
|
149301-79-1
|
98%
|
|
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid. It is a potent and selective slow binding inh...
|
TN7075 |
Linocinnamarin
|
554-87-0
|
99.95%
|
|
Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen...
|
T3616 |
Carbazochrome
|
69-81-8
|
99.95%
|
|
Carbazochrome (Adchnon) is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood ...
|
T8531 |
M-3M3FBS
|
200933-14-8
|
99.92%
|
|
m-3M3FBS is a phospholipase C (PLC) activator.
|
T6109 |
Darapladib
|
356057-34-6
|
99.85%
|
|
Darapladib (SB-480848)(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2).
|
T6529 |
Halobetasol propionate
|
66852-54-8
|
99.85%
|
|
Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrict...
|
T0674 |
Lansoprazole
|
103577-45-3
|
99.84%
|
|
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME...
|
T0693 |
Niflumic acid
|
4394-00-7
|
99.79%
|
|
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
|
TP1299L1 |
Melittin Acetate
|
|
99.78%
|
|
Melittin Acetate (Forapin Acetate) is a PLA2 activator. Melittin Acetate stimulates the activity of the low molecular weight PLA2, while it does not increase the...
|
T4S0590 |
Columbin
|
546-97-4
|
99.74%
|
|
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC...
|
TN4893 |
Rapanone
|
573-40-0
|
99.72%
|
|
Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.
|
T8966 |
ML-298
|
1426916-02-0
|
99.7%
|
|
ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).
|
T17218 |
Varespladib methyl
|
172733-08-3
|
99.69%
|
|
Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.
|
T31929 |
Giripladib
|
865200-20-0
|
99.68%
|
|
Giripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endotheli...
|
T10168 |
5-HT1A modulator 1
|
142477-34-7
|
99.66%
|
|
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
|
T3640 |
GW4869
|
6823-69-4
|
99.66%
|
|
GW4869 (GW69A) is a noncompetitive inhibitor of neutral sphingomyelinase (N-SMase, IC50 of 1 μM). GW4869(GW 4869) is an exosome biogenesis/release inhibitor.
|
T0188 |
Fluticasone (propionate)
|
80474-14-2
|
99.65%
|
|
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid recep...
|
T67749 |
Fuzapladib
|
141283-87-6
|
99.65%
|
|
Fuzapladib (IS-741) (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of...
|