T78977 |
Antitrypanosomal agent 12
|
|
98%
|
|
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.22...
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T78978 |
Antitrypanosomal agent 13
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|
98%
|
|
Compound 4b (antitrypanosomal agent 13) is a potent antitrypanosomal with notable trypanocidal and cytotoxic activities, exhibiting GI50 values of 0.18 μM agains...
|
T79122 |
Insecticidal agent 2
|
201593-85-3
|
98%
|
|
Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].
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T79253 |
HAT-IN-8
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98%
|
|
HAT-IN-8 (Compound 38), a blood-brain barrier-permeable inhibitor of Trypanosoma brucei with an EC50 of 0.18 μM, is utilized in the study of Human African trypan...
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T79254 |
Antitrypanosomal agent 14
|
1447933-37-0
|
98%
|
|
Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 μM, also inhibits Tb GSK3 with an inhibitory ...
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T79277 |
Cysteine protease inhibitor-3
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|
98%
|
|
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM), PfW...
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T79301 |
Anticancer agent 140
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|
98%
|
|
Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].
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T79335 |
Antimalarial agent 31
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|
98%
|
|
Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].
|
T79390 |
Antileishmanial agent-23
|
745033-86-7
|
98%
|
|
Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM. It effectively inhib...
|
T79415 |
Antiparasitic agent-18
|
2821884-59-5
|
98%
|
|
Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cr...
|
T79419 |
Antileishmanial agent-24
|
|
98%
|
|
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM against amastigote...
|
T79449 |
Antileishmanial agent-19
|
|
98%
|
|
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 μM. It function...
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T79460 |
Antimalarial agent 28
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|
98%
|
|
Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P. berghei with IC50 values of 0.561 μM for the liver stage, 0.14 μ...
|
T79471 |
Antileishmanial agent-20
|
|
98%
|
|
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L. infantum and 0.2 μM for L. braziliensis. It is a...
|
T79534 |
Antimalarial agent 29
|
2821078-81-1
|
98%
|
|
Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P. berghei liver stage parasite load, exhibiting an effectiv...
|
T79568 |
NPD-2975
|
|
98%
|
|
NPD-2975 (compound 30) is an orally active antitrypanosomal agent effective against Human African Trypanosomiasis (HAT), demonstrating acceptable metabolic stabi...
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T79632 |
Antileishmanial agent-21
|
|
98%
|
|
Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism. Its antileish...
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T79633 |
Antileishmanial agent-22
|
|
98%
|
|
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tu...
|
T79690 |
FIKK9.1-IN-1
|
1448523-50-9
|
98%
|
|
FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1, t...
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T79703 |
RyRs activator 3
|
2850333-35-4
|
98%
|
|
RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M. separata and P. xylostella. It exhibits an LC50 o...
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