PKA

protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase . Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

Cat. No.	Product name	CAS No.	Purity
T7648	HA-100	84468-24-6	99.69%
T7648	HA-100 is an inhibitor of protein kinase
T6304	AT7867	857531-00-1	99.65%
T6304	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the...
T3050	ML-7 hydrochloride	110448-33-4	99.61%
T3050	ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also...
T75888	PKA Inhibitor Fragment (6-22) amide TFA		99.61%
T75888	PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhi...
T1418	Bucladesine sodium	16980-89-5	99.58%
T1418	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a pho...
T6139L	A-674563 2HCl(552325-73-2(fb-2hcl))	T6139L	99.57%
T6139L	A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
T3060	Fasudil hydrochloride	105628-07-7	99.54%
T3060	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T19836	2-Aminopurine	452-06-2	99.51%
T19836	2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.
TP1957L	PKI (5-24) Acetate(99534-03-9 free base)	TP1957L	99.47%
TP1957L	PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM).
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	40732-48-7	99.44%
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. It...
T6250	H-89 dihydrochloride	130964-39-5	99.4%
T6250	H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).
T0610	Piceatannol	10083-24-6	99.39%
T0610	Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits...
T1837	BX-912	702674-56-4	99.34%
T1837	BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC...
T77504	JAK1/2/3 Inhibitor 1	16234-14-3	99.32%
T77504	JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines....
T21674L	PKA inhibitor fragment (6-22) amide Acetate	T21674L	99.30%
T21674L	PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).
TP1787L	PKG Substrate acetate（81187-14-6 free base)	TP1787L	99.30%
TP1787L	PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a s...
T1920	Capivasertib	1143532-39-1	99.29%
T1920	Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib h...
T6139	A-674563	552325-73-2	99.21%
T6139	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
T6303	CCT128930	885499-61-6	99.18%
T6303	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinas...
T6315	MLN8054	869363-13-3	99.05%
T6315	MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.