T2591 |
Veliparib
|
912444-00-9
|
99.76%
|
|
Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.
|
T5399 |
GeA-69
|
2143475-98-1
|
99.75%
|
|
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
|
TN2329 |
Zingiberen newsaponin
|
91653-50-8
|
99.75%
|
|
Zingiberen newsaponin is a steroidal saponin from Dioscorea zingiberensis.
|
TN1153 |
Polyporenic acid C
|
465-18-9
|
99.71%
|
|
Polyporenic acid C shows inhibitory activity against human collagenase.
|
T61932 |
Nesuparib
|
2055357-64-5
|
99.71%
|
|
Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatmen...
|
T73007 |
PARP10-IN-2
|
1042780-52-8
|
99.68%
|
|
PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and P...
|
T15639 |
K-756
|
130017-40-2
|
99.68%
|
|
K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 (IC50s: 31 and 36 nM, respectivel...
|
T6780 |
Benzamide
|
55-21-0
|
99.64%
|
|
Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.
|
T9113 |
Myristicin
|
607-91-0
|
99.63%
|
|
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effe...
|
T7896 |
BYK204165
|
1104546-89-5
|
99.61%
|
|
BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)
|
T3062 |
WIKI4
|
838818-26-1
|
99.6%
|
|
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).
|
T12365 |
PARP/PI3K-IN-1
|
2337386-47-5
|
99.59%
|
|
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antipr...
|
T3649 |
BGP-15
|
66611-37-8
|
99.59%
|
|
BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.
|
T16761 |
RK-287107
|
2171386-10-8
|
99.59%
|
|
RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).
|
T3261 |
NVP-TNKS656
|
1419949-20-4
|
99.55%
|
|
NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.
|
T67932 |
PARP10-IN-3
|
2225800-19-9
|
99.54%
|
|
PARP10-IN-3 is a potent and selective mono-Adp-ribotransferase PARP10 inhibitor that inhibits human PARP10 (IC50:480 nM). PARP10-IN-3 also inhibited human PARP2 ...
|
T5058 |
Pamiparib
|
1446261-44-4
|
99.53%
|
|
Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP...
|
T22988 |
MK-4827 Racemate
|
1038915-75-1
|
99.47%
|
|
MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3...
|
T60039 |
KSQ-4279
|
2446480-97-1
|
99.43%
|
|
KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma, ovar...
|
T7042 |
1,5-Isoquinolinediol
|
5154-02-9
|
99.43%
|
|
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes wi...
|