T7472 |
7-Hydroxyflavone
|
6665-86-7
|
98%
|
|
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2.with anti-inflammator...
|
T7132 |
(Rac)-Brassinazole
|
224047-41-0
|
98%
|
|
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell divisio...
|
T5594 |
Cedrol
|
77-53-2
|
98%
|
|
Cedrol is a cedrane sesquiterpenoid and a tertiary alcohol,Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respective...
|
T2305 |
Isavuconazole
|
241479-67-4
|
98%
|
|
Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004...
|
T8125 |
Quinidine sulfate dihydrate
|
6591-63-5
|
98%
|
|
Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor
|
T7427 |
1-Ethynylnaphthalene
|
15727-65-8
|
98%
|
|
1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 IB1
|
T12146 |
N-Desmethyl-Apalutamide
|
1332391-11-3
|
97.83%
|
|
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
|
T6246 |
Cobicistat
|
1004316-88-4
|
97.79%
|
|
Cobicistat (GS-9350) is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, ...
|
TN1702 |
Glycycoumarin
|
94805-82-0
|
97.64%
|
|
Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.
|
T3696 |
Polygalaxanthone III
|
162857-78-5
|
97.54%
|
|
Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
|
T2196 |
Fipronil
|
120068-37-3
|
97.48%
|
|
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disr...
|
T30161 |
EN3356
|
1429329-63-4
|
97.47%
|
|
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzym...
|
T37332 |
(±)-N-3-Benzylnirvanol
|
93879-40-4
|
97.16%
|
|
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll. (+) -n-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll are sele...
|
T26322L |
(-)-Vorozole
|
132042-69-4
|
97.14%
|
|
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
|
T4188 |
SDZ285428
|
174262-13-6
|
96.91%
|
|
SDZ285428 is a CYP24A1 inhibitor.
|
T50001 |
Tinoridine
|
24237-54-5
|
95.00%
|
|
Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and antic...
|
T50053 |
Lofemizole
|
65571-68-8
|
95.00%
|
|
Lofemizole is an antagonist of CYP1A2.
|
T5S2343 |
Acetylshikonin
|
24502-78-1
|
92.45%
|
|
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and a...
|
T3002 |
Piperine
|
94-62-2
|
100%
|
|
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.
|
T23549 |
YM 511
|
148869-05-0
|
100%
|
|
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
|