T13600 |
CDD3505
|
173865-33-3
|
99.39%
|
|
CDD3505 (4-nitro-1-trityl-1H-imidazole) increases high-density lipoprotein cholesterol by targeting hepatic CYP3A.
|
T3886 |
Rosavin
|
84954-92-7
|
99.38%
|
|
Rosavin (Rosavidin) has antidepressant and anxiolytic actions, helps balance all the neurotransmitters.
|
T11847L |
Liarozole
|
115575-11-6
|
99.38%
|
|
Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of ar...
|
T3735 |
Tetrahydrocurcumin
|
36062-04-1
|
99.37%
|
|
Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.
|
T9113 |
Myristicin
|
607-91-0
|
99.34%
|
|
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effe...
|
T6S1917 |
Schisandrol B
|
58546-54-6
|
99.32%
|
|
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated...
|
T12171 |
Nampt-IN-5
|
2380013-17-0
|
99.3%
|
|
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
|
T1491 |
Atovaquone
|
95233-18-4
|
99.28%
|
|
Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
|
T6260 |
AMG-208
|
1002304-34-8
|
99.27%
|
|
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
|
TP1313L |
Cecropin B acetate
|
|
99.27%
|
|
Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA se...
|
T2840 |
Phloracetophenone
|
480-66-0
|
99.26%
|
|
Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of...
|
T77627 |
Opevesostat
|
2231294-96-3
|
99.25%
|
|
Opevesostat (ODM-208) is an inhibitor of lyase (CYP11A1) (the enzyme cleavage cholesterol side chain).
|
T11680 |
Isoasatone A
|
67451-73-4
|
99.21%
|
|
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.
|
T10923 |
CYP17-IN-1
|
2093317-51-0
|
99.17%
|
|
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
|
T2761 |
Naringin dihydrochalcone
|
18916-17-1
|
99.16%
|
|
Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
|
T9043 |
AS1810722
|
909561-15-5
|
99.13%
|
|
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhi...
|
T0865 |
Ranitidine Hydrochloride
|
66357-59-3
|
99.13%
|
|
Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversibl...
|
T3610 |
Ranitidine
|
66357-35-5
|
99.1%
|
|
Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestina...
|
T35716 |
N-desmethyl Olanzapine
|
161696-76-0
|
99.1%
|
|
N-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the ...
|
T21507 |
7-Ethoxyresorufin
|
5725-91-7
|
99.09%
|
|
7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.
|