T8125 |
Quinidine sulfate dihydrate
|
6591-63-5
|
98%
|
|
Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor
|
T7427 |
1-Ethynylnaphthalene
|
15727-65-8
|
98%
|
|
1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 IB1
|
T12146 |
N-Desmethyl-Apalutamide
|
1332391-11-3
|
97.83%
|
|
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
|
TN1702 |
Glycycoumarin
|
94805-82-0
|
97.64%
|
|
Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.
|
T30161 |
EN3356
|
1429329-63-4
|
97.47%
|
|
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzym...
|
TJS1159 |
Chrysosplenetin
|
603-56-5
|
97.43%
|
|
Chrysosplenetin is a metabolic inhibitor of artemisinin.
|
T0660 |
Beta-Tetralone
|
530-93-8
|
97.26%
|
|
Beta-Tetralone (2-Tetralone) is a ketone derivative of tetralin.
|
T37332 |
(±)-N-3-Benzylnirvanol
|
93879-40-4
|
97.16%
|
|
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll. (+) -n-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll are sele...
|
T26322L |
(-)-Vorozole
|
132042-69-4
|
97.14%
|
|
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
|
T4188 |
SDZ285428
|
174262-13-6
|
96.91%
|
|
SDZ285428 is a CYP24A1 inhibitor.
|
T50001 |
Tinoridine
|
24237-54-5
|
95.00%
|
|
Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and antic...
|
T50053 |
Lofemizole
|
65571-68-8
|
95.00%
|
|
Lofemizole is an antagonist of CYP1A2.
|
T5S2343 |
Acetylshikonin
|
24502-78-1
|
92.45%
|
|
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and a...
|
T3002 |
Piperine
|
94-62-2
|
100%
|
|
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.
|
T23549 |
YM 511
|
148869-05-0
|
100%
|
|
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
|
T1011 |
Itraconazole
|
84625-61-6
|
100%
|
|
Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
|
T1704 |
Diosmetin
|
520-34-3
|
100%
|
|
Diosmetin (Luteolin 4-methyl ether) has been found to act as a weak TrkB receptor agonist.
|
T3797 |
Isosilybin
|
72581-71-6
|
100%
|
|
Isosilybin (Isosilibinin) and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patien...
|
TN1724 |
Harmalol hydrochloride
|
6028-07-5
|
100%
|
|
Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is th...
|
T7725 |
Albaconazole
|
187949-02-6
|
100%
|
|
Albaconazole (W-0027) is a small molecule fungal cytochrome P450 family member 51 (fungal CYP51A1) inhibitor. It is used in the treatment of fungal infections, s...
|