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Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0543 7-Methylxanthine 552-62-5 98.58%
7-Methylxanthine
7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM i...
T36572 N6-Methyladenine 443-72-1 98.35%
N6-Methyladenine
N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DN...
T19152 5-OHdU 5168-36-5 98.32%
5-OHdU
5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.
T9605 Sangivamycin 18417-89-5 98.11%
Sangivamycin
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of h...
T15235 Enocitabine 55726-47-1 98.02%
Enocitabine
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. En...
T7518 Deoxycytidine triphosphate trisodium salt 109909-44-6 98%
Deoxycytidine triphosphate trisodium salt
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.
T7491 6-O-Methyl Guanosine 7803-88-5 98%
6-O-Methyl Guanosine
6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.
T1428 Trifluridine 70-00-8 98%
Trifluridine
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate...
T7351 3-Methylcytidine 2140-64-9 98%
3-Methylcytidine
3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.
T7514 N2-Methylguanosine 2140-77-4 98%
N2-Methylguanosine
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
T6603 Nelarabine 121032-29-9 97.90%
Nelarabine
Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
T7520 Deoxycytidine triphosphate 2056-98-6 95.19%
Deoxycytidine triphosphate
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-tim...
T10019 1-Methylcytosine 1122-47-0 100%
1-Methylcytosine
1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isogua...
T1506 Vidarabine 5536-17-4 100%
Vidarabine
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum...
T1038 Fludarabine 21679-14-1 100%
Fludarabine
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor...
T7621 6-​Thioinosine 574-25-4 100%
6-​Thioinosine
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.
T3271 Orotic acid zinc 68399-76-8 100%
Orotic acid zinc
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
T8354 Triazavirin 928659-17-0 100%
Triazavirin
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T0297 Clofarabine 123318-82-1 100%
Clofarabine
Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase...
T6794 5-BrdU 59-14-3 100%
5-BrdU
5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.
7-Methylxanthine
T0543
7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM i...
N6-Methyladenine
T36572
N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DN...
5-OHdU
T19152
5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.
Sangivamycin
T9605
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of h...
Enocitabine
T15235
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. En...
Deoxycytidine triphosphate trisodium salt
T7518
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.
6-O-Methyl Guanosine
T7491
6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.
Trifluridine
T1428
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate...
3-Methylcytidine
T7351
3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.
N2-Methylguanosine
T7514
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
Nelarabine
T6603
Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
Deoxycytidine triphosphate
T7520
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-tim...
1-Methylcytosine
T10019
1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isogua...
Vidarabine
T1506
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum...
Fludarabine
T1038
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor...
6-​Thioinosine
T7621
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.
Orotic acid zinc
T3271
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
Triazavirin
T8354
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
Clofarabine
T0297
Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase...
5-BrdU
T6794
5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.
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TargetMol