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Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T3658 Trifluridine/tipiracil hydrochloride mixture 733030-01-8 99.82%
Trifluridine/tipiracil hydrochloride mixture
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
TNU0355 N6-Methyl-2'-O-methyladenosine 57817-83-1 99.77%
N6-Methyl-2'-O-methyladenosine
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on...
T13621 CNDAC hydrochloride 134665-72-8 99.69%
CNDAC hydrochloride
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
T1339 5-Azacytidine 320-67-2 99.62%
5-Azacytidine
5-Azacytidine (Ladakamycin) , a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity.
T38251 L-Uridine 26287-69-4 99.57%
L-Uridine
L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a norm...
TNU0266 9-(β-D-Xylofuranosyl)adenine 524-69-6 99.55%
9-(β-D-Xylofuranosyl)adenine
9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has an...
T16813 RX-3117 865838-26-2 99.55%
RX-3117
RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resi...
T36687 Ac-rC Phosphoramidite 121058-88-6 99.49%
Ac-rC Phosphoramidite
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
T22337 Ganciclovir sodium 107910-75-8 99.47%
Ganciclovir sodium
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex vi...
T2366 Tipiracil hydrochloride 183204-72-0 99.45%
Tipiracil hydrochloride
Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102, wh...
TNU0541 8-Azaguanosine 2133-80-4 99.44%
8-Azaguanosine
8-Azaguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity and is used in the study of a variety of tumor diseases.
TNU0085 2'-Deoxy-2'-fluoroarabinoadenosine 20227-41-2 99.44%
2'-Deoxy-2'-fluoroarabinoadenosine
2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.
T19464 N6,N6-Dimethyladenosine 2620-62-4 99.42%
N6,N6-Dimethyladenosine
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
T4061 LY2334737 892128-60-8 99.4%
LY2334737
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T0532 5,6-Dihydro-5-methyluracil 696-04-8 99.37%
5,6-Dihydro-5-methyluracil
5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.
TNU0091 3'-Deoxy-3'-fluoroguanosine 123402-21-1 99.33%
3'-Deoxy-3'-fluoroguanosine
3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to tr...
T14329 Ascamycin 91432-48-3 99.29%
Ascamycin
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
T12399 Peldesine 133432-71-0 99.27%
Peldesine
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferat...
T65979 Adenosine 5'-monophosphate disodium salt 4578-31-8 99.24%
Adenosine 5'-monophosphate disodium salt
Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP...
T1508 Decitabine 2353-33-5 99.17%
Decitabine
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic a...
Trifluridine/tipiracil hydrochloride mixture
T3658
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
N6-Methyl-2'-O-methyladenosine
TNU0355
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on...
CNDAC hydrochloride
T13621
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
5-Azacytidine
T1339
5-Azacytidine (Ladakamycin) , a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity.
L-Uridine
T38251
L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a norm...
9-(β-D-Xylofuranosyl)adenine
TNU0266
9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has an...
RX-3117
T16813
RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resi...
Ac-rC Phosphoramidite
T36687
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
Ganciclovir sodium
T22337
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex vi...
Tipiracil hydrochloride
T2366
Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102, wh...
8-Azaguanosine
TNU0541
8-Azaguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity and is used in the study of a variety of tumor diseases.
2'-Deoxy-2'-fluoroarabinoadenosine
TNU0085
2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.
N6,N6-Dimethyladenosine
T19464
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
LY2334737
T4061
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
5,6-Dihydro-5-methyluracil
T0532
5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.
3'-Deoxy-3'-fluoroguanosine
TNU0091
3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to tr...
Ascamycin
T14329
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
Peldesine
T12399
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferat...
Adenosine 5'-monophosphate disodium salt
T65979
Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP...
Decitabine
T1508
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic a...
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