T4S1050 |
Pristimerin
|
1258-84-0
|
99.59%
|
|
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced m...
|
T8550 |
NDMC101
|
1308631-40-4
|
99.59%
|
|
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 a...
|
T9115 |
Vanillic Acid
|
121-34-6
|
99.58%
|
|
Vanillic Acid (Acide vanillique) is used as a condiment in food,which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic ...
|
T3729 |
Ethyl gallate
|
831-61-8
|
99.58%
|
|
Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytot...
|
T24816 |
SP-100030
|
154563-54-9
|
99.57%
|
|
SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha prod...
|
T13686 |
Ergolide
|
54999-07-4
|
99.56%
|
|
Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and...
|
T3S1692 |
Octahydrocurcumin
|
36062-07-4
|
99.54%
|
|
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
|
TN4220 |
Homobutein
|
34000-39-0
|
99.50%
|
|
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammato...
|
T3S1775 |
Tectochrysin
|
520-28-5
|
99.49%
|
|
1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrys...
|
T16290 |
NIK SMI1
|
1660114-31-7
|
99.48%
|
|
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).
|
TN1410 |
Asperulosidic acid
|
25368-11-0
|
99.47%
|
|
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-...
|
T17309 |
(R)-(-)-Ibuprofen
|
51146-57-7
|
99.47%
|
|
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive eff...
|
TN1035 |
Irisolidone
|
2345-17-7
|
99.46%
|
|
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
|
T6027 |
Delanzomib
|
847499-27-8
|
99.46%
|
|
Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and ...
|
T6S0659 |
Rhynchophylline
|
76-66-4
|
99.44%
|
|
1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against gluta...
|
T3662 |
Eleutheroside E
|
39432-56-9
|
99.43%
|
|
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus ...
|
T1934 |
Bay 11-7085
|
196309-76-9
|
99.43%
|
|
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
|
TN2008 |
Okanin
|
484-76-4
|
99.4%
|
|
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.
|
T2920 |
Berbamine dihydrochloride
|
6078-17-7
|
99.38%
|
|
Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.
|
T6S0119 |
Dauricine
|
524-17-4
|
99.38%
|
|
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood...
|