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Monoamine Oxidase

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. The MAOs belong to the protein family of flavin-containing amine oxidoreductases.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78127 Tisolagiline 1894207-44-3 98%
Tisolagiline
Tisolagiline (KDS2010), a reversible MAO-B inhibitor, is utilized in Parkinson's disease research [1].
T78648 MAO-B-IN-3 98%
MAO-B-IN-3
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki o...
T78649 MAO-B-IN-4 98%
MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM. This orally...
T78690 MAO-B-IN-18 98%
MAO-B-IN-18
MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects aga...
T78793 MAOA-IN-1 98%
MAOA-IN-1
MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells. This compound demon...
T78821 IHC3 98%
IHC3
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site. It is ...
T78848 MAO-IN-3 797805-26-6 98%
MAO-IN-3
MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B, e...
T78859 MAO-B-IN-23 2107978-22-1 98%
MAO-B-IN-23
MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM ...
T78860 MAO-B-IN-24 98%
MAO-B-IN-24
MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM. It also exhibits inhibitory effects on MAO-A...
T78889 Lysyl hydroxylase 2-IN-1 98%
Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity f...
T78898 Lysyl hydroxylase 2-IN-2 98%
Lysyl hydroxylase 2-IN-2
Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM. It effectively inhibits ce...
T78907 MAO-B-IN-22 2902600-76-2 98%
MAO-B-IN-22
MAO-B-IN-22 (compound 6h) represents a powerful MAO-B inhibitor, boasting an IC50 value of 0.014 μM, and exhibits high antioxidant activity alongside effective m...
T79229 ETAP 2575731-47-2 98%
ETAP
ETAP, a dual inhibitor of both monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B), exhibits antidepressant-like effects and is utilized in the research ...
T79299 HAChE-IN-3 98%
hAChE-IN-3
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM, demonstra...
T79486 MAO A/HSP90-IN-1 2927489-95-8 98%
MAO A/HSP90-IN-1
MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α. Th...
T79487 MAO A/HSP90-IN-2 2927489-99-2 98%
MAO A/HSP90-IN-2
MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90. This compound not only en...
T79761 MAO-B-IN-25 98%
MAO-B-IN-25
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM ...
T79914 Tranylcypromine 155-09-9 98%
Tranylcypromine
Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.
T79979 Methyl piperate 6190-46-1 98%
Methyl piperate
Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition ...
T80634 MAO-B-IN-19 152897-41-1 98%
MAO-B-IN-19
MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].
Tisolagiline
T78127
Tisolagiline (KDS2010), a reversible MAO-B inhibitor, is utilized in Parkinson's disease research [1].
MAO-B-IN-3
T78648
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki o...
MAO-B-IN-4
T78649
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM. This orally...
MAO-B-IN-18
T78690
MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects aga...
MAOA-IN-1
T78793
MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells. This compound demon...
IHC3
T78821
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site. It is ...
MAO-IN-3
T78848
MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B, e...
MAO-B-IN-23
T78859
MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM ...
MAO-B-IN-24
T78860
MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM. It also exhibits inhibitory effects on MAO-A...
Lysyl hydroxylase 2-IN-1
T78889
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity f...
Lysyl hydroxylase 2-IN-2
T78898
Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM. It effectively inhibits ce...
MAO-B-IN-22
T78907
MAO-B-IN-22 (compound 6h) represents a powerful MAO-B inhibitor, boasting an IC50 value of 0.014 μM, and exhibits high antioxidant activity alongside effective m...
ETAP
T79229
ETAP, a dual inhibitor of both monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B), exhibits antidepressant-like effects and is utilized in the research ...
hAChE-IN-3
T79299
hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM, demonstra...
MAO A/HSP90-IN-1
T79486
MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α. Th...
MAO A/HSP90-IN-2
T79487
MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90. This compound not only en...
MAO-B-IN-25
T79761
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM ...
Tranylcypromine
T79914
Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.
Methyl piperate
T79979
Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition ...
MAO-B-IN-19
T80634
MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].
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TargetMol