T6223 |
U0126-EtOH
|
1173097-76-1
|
98.65%
|
|
U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).
|
T1879 |
3-Methyladenine
|
5142-23-4
|
98.44%
|
|
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM). 3-Methyladenine inhibits autop...
|
T1907 |
Mdivi-1
|
338967-87-6
|
98.24%
|
|
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondria...
|
T0374 |
Sunitinib Malate
|
341031-54-7
|
98.23%
|
|
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-...
|
T0374L |
Sunitinib
|
557795-19-4
|
98.22%
|
|
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM). Sunitinib has antitumor activit...
|
T0876 |
Clioquinol
|
130-26-7
|
98.09%
|
|
Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potent...
|
T2174 |
Quercetin
|
117-39-5
|
98.05%
|
|
Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1. Quercetin is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ (IC50=2.4/3.0/5....
|
T1477 |
AICAR
|
2627-69-2
|
98.00%
|
|
AICAR (NSC105823) is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treat...
|
T0947 |
Dexamethasone acetate
|
1177-87-3
|
98%
|
|
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
|
T6714 |
URB-597
|
546141-08-6
|
97.84%
|
|
URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.
|
T2870 |
Matrine
|
519-02-8
|
97.16%
|
|
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
|
T12352 |
Oxidopamine hydrochloride
|
28094-15-7
|
96.17%
|
|
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.
|
T1131 |
Ivermectin
|
70288-86-7
|
95.35%
|
|
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
|
T1554 |
Iohexol
|
66108-95-0
|
80.18%
|
|
Iohexol is a contrast agent. The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times th...
|
T0005 |
Aspirin
|
50-78-2
|
100%
|
|
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Asp...
|
T5515 |
Hemin
|
16009-13-5
|
|
|
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme...
|
T2830 |
Betulinic acid
|
472-15-1
|
|
|
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
|
T0972 |
Isoniazid
|
54-85-3
|
98%
|
|
Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic.
|
T12352L |
Oxidopamine hydrobromide
|
636-00-0
|
98%
|
|
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.
|
T14149 |
AICAR phosphate
|
681006-28-0
|
98%
|
|
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose ...
|