T9232 |
Mitochondrial fusion promoter M1
|
219315-22-7
|
99.54%
|
|
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in redu...
|
T6834 |
FCCP
|
370-86-5
|
99.5%
|
|
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is of...
|
T2970 |
Rotenone
|
83-79-4
|
99.48%
|
|
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the produc...
|
T9031 |
MCU-i4
|
371924-24-2
|
99.45%
|
|
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
|
T2607 |
MSDC 0160
|
146062-49-9
|
99.45%
|
|
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
|
TN1362 |
Afzelin
|
482-39-3
|
99.38%
|
|
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absor...
|
T2988 |
(-)-Epigallocatechin Gallate
|
989-51-5
|
99.34%
|
|
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG...
|
T16342 |
KL1333
|
1800405-30-4
|
99.27%
|
|
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and...
|
T6157 |
Devimistat
|
95809-78-2
|
99.24%
|
|
Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, ...
|
T8433 |
HQNO
|
341-88-8
|
99.23%
|
|
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mit...
|
T2498 |
Adjudin
|
252025-52-8
|
99.05%
|
|
Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
|
T9235 |
GW604714X
|
853953-65-8
|
99.03%
|
|
GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitoch...
|
T77621 |
Z16078526
|
852222-94-7
|
98.93%
|
|
Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse b...
|
T4446 |
Tebufenpyrad
|
119168-77-3
|
98.92%
|
|
Tebufenpyrad (Comanche) (mitochondrial complex-1 inhibitors) is an agro-chemically important acaricide that functions like the known mitochondrial toxicant roten...
|
T0412 |
Idebenone
|
58186-27-9
|
98.76%
|
|
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC)....
|
T9774 |
BAY-179
|
2764880-87-5
|
98.75%
|
|
BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.
|
T7081 |
CCCP
|
555-60-2
|
98.55%
|
|
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
|
T8308 |
NL-1
|
188532-26-5
|
98.42%
|
|
NL-1 is a mitoNEET inhibitor with antileukemic effect.
|
T0200 |
α-Lipoic Acid
|
1077-28-7
|
98.39%
|
|
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is bio...
|
T5363 |
Tempo
|
2564-83-2
|
98.35%
|
|
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a stru...
|