T9411 |
KX2-361
|
897016-26-1
|
98.52%
|
|
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
|
T2937 |
4'-Demethylepipodophyllotoxin
|
6559-91-7
|
98.49%
|
|
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
|
T6897 |
Monomethyl auristatin E
|
474645-27-7
|
98.47%
|
|
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody...
|
T8216 |
T-1101 tosylate
|
2250404-95-4
|
98.47%
|
|
T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.
|
T21351 |
Maytansine
|
35846-53-8
|
98.43%
|
|
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding ...
|
T2217 |
Cephalomannine
|
71610-00-9
|
98.38%
|
|
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
|
T77342 |
GSK-3 inhibitor 3
|
2227279-84-5
|
98.36%
|
|
GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively....
|
T10460 |
Batabulin
|
195533-53-0
|
98.35%
|
|
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polyme...
|
T0838 |
Triclabendazole
|
68786-66-3
|
98.35%
|
|
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
|
T67935 |
Tubulin inhibitor 11
|
2366260-33-3
|
98.32%
|
|
Tubulin inhibitor 11 is a potent and orally active tubulin inhibitor. Tubulin inhibitor 11 targets the Colchicine binding site on tubulin, inhibits tubulin polym...
|
T6490 |
Epothilone A
|
152044-53-6
|
98.27%
|
|
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
|
T6212 |
Combretastatin A4
|
117048-59-6
|
98.21%
|
|
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
|
T15012 |
Crolibulin
|
1000852-17-4
|
98.19%
|
|
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
|
TN2254 |
Taccalonolide A
|
108885-68-3
|
98.16%
|
|
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
|
T15141 |
DM4
|
796073-69-3
|
98.15%
|
|
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
|
T2543 |
Cabazitaxel
|
183133-96-2
|
98.14%
|
|
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after...
|
T67964 |
Terflavoxate
|
86433-40-1
|
98.07%
|
|
Terflavoxate is a novel, orally active, semi-synthetic statin microtubule inhibitor often used in combination with capecitabine. Terflavoxate is a potential comp...
|
T16788 |
Rosabulin
|
501948-05-6
|
98.06%
|
|
v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity....
|
T6372 |
Albendazole sulfoxide
|
54029-12-8
|
98.04%
|
|
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
|
T15612 |
JH-VIII-157-02
|
1639422-97-1
|
98.02%
|
|
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-A...
|