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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T9411 KX2-361 897016-26-1 98.52%
KX2-361
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
T2937 4'-Demethylepipodophyllotoxin 6559-91-7 98.49%
4'-Demethylepipodophyllotoxin
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
T6897 Monomethyl auristatin E 474645-27-7 98.47%
Monomethyl auristatin E
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody...
T8216 T-1101 tosylate 2250404-95-4 98.47%
T-1101 tosylate
T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.
T21351 Maytansine 35846-53-8 98.43%
Maytansine
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding ...
T2217 Cephalomannine 71610-00-9 98.38%
Cephalomannine
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
T77342 GSK-3 inhibitor 3 2227279-84-5 98.36%
GSK-3 inhibitor 3
GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively....
T10460 Batabulin 195533-53-0 98.35%
Batabulin
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polyme...
T0838 Triclabendazole 68786-66-3 98.35%
Triclabendazole
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
T67935 Tubulin inhibitor 11 2366260-33-3 98.32%
Tubulin inhibitor 11
Tubulin inhibitor 11 is a potent and orally active tubulin inhibitor. Tubulin inhibitor 11 targets the Colchicine binding site on tubulin, inhibits tubulin polym...
T6490 Epothilone A 152044-53-6 98.27%
Epothilone A
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
T6212 Combretastatin A4 117048-59-6 98.21%
Combretastatin A4
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
T15012 Crolibulin 1000852-17-4 98.19%
Crolibulin
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
TN2254 Taccalonolide A 108885-68-3 98.16%
Taccalonolide A
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
T15141 DM4 796073-69-3 98.15%
DM4
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
T2543 Cabazitaxel 183133-96-2 98.14%
Cabazitaxel
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after...
T67964 Terflavoxate 86433-40-1 98.07%
Terflavoxate
Terflavoxate is a novel, orally active, semi-synthetic statin microtubule inhibitor often used in combination with capecitabine. Terflavoxate is a potential comp...
T16788 Rosabulin 501948-05-6 98.06%
Rosabulin
v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity....
T6372 Albendazole sulfoxide 54029-12-8 98.04%
Albendazole sulfoxide
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
T15612 JH-VIII-157-02 1639422-97-1 98.02%
JH-VIII-157-02
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-A...
KX2-361
T9411
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
4'-Demethylepipodophyllotoxin
T2937
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
Monomethyl auristatin E
T6897
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody...
T-1101 tosylate
T8216
T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.
Maytansine
T21351
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding ...
Cephalomannine
T2217
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
GSK-3 inhibitor 3
T77342
GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively....
Batabulin
T10460
Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polyme...
Triclabendazole
T0838
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
Tubulin inhibitor 11
T67935
Tubulin inhibitor 11 is a potent and orally active tubulin inhibitor. Tubulin inhibitor 11 targets the Colchicine binding site on tubulin, inhibits tubulin polym...
Epothilone A
T6490
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
Combretastatin A4
T6212
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
Crolibulin
T15012
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
Taccalonolide A
TN2254
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
DM4
T15141
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Cabazitaxel
T2543
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after...
Terflavoxate
T67964
Terflavoxate is a novel, orally active, semi-synthetic statin microtubule inhibitor often used in combination with capecitabine. Terflavoxate is a potential comp...
Rosabulin
T16788
v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity....
Albendazole sulfoxide
T6372
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
JH-VIII-157-02
T15612
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-A...
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TargetMol