Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.

Cat. No.	Product name	CAS No.	Purity
T1753	D-64131	74588-78-6	99.58%
T1753	D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.
T67769	MPT0B014	1215208-59-5	99.56%
T67769	MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.
T6075	Epothilone B	152044-54-7	99.54%
T6075	Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization a...
T5165	10-Deacetyltaxol	78432-77-6	99.54%
T5165	10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.
T13224	Tubulin inhibitor 6	105925-39-1	99.53%
T13224	Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.
T10772	Cevipabulin	849550-05-6	99.53%
T10772	Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell ...
T1155	Mebendazole	31431-39-7	99.51%
T1155	Mebendazole (Mebenvet) is a hedgehog inhibitor, used as an antihelminthic.
T68490	CMPF	86879-39-2	99.5%
T68490	CMPF is a microtubule protein inhibitor that can be used to study tumors.
T9831	MKC-1	125313-92-0	99.46%
T9831	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its meta...
T61661	LY3372689	2241514-56-5	99.45%
T61661	LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.
T77584	Tubulin inhibitor 35	2247047-77-2	99.45%
T77584	Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migra...
T26585	AK301	314022-97-4	99.45%
T26585	AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cance...
T15675	Tirbanibulin Mesylate	1080645-95-9	99.42%
T15675	Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
T1668	Vinblastine sulfate	143-67-9	99.38%
T1668	Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
T67834	C004019	2417159-57-8	99.37%
T67834	C004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from the cell, while recruiting tau and E3 ligase (Vhl) for selecti...
T15205	EL-102	1233948-61-2	99.34%
T15205	EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.
T2802	Nocodazole	31430-18-9	99.34%
T2802	Nocodazole (Oncodazole) is a reversible inhibitor of microtubule polymerization and an inhibitor of Bcr-Abl. Nocodazole has antitumor activity, blocks the cell c...
T13226	Tubulin inhibitor 8	1309925-39-0	99.34%
T13226	Tubulin inhibitor 8 is an inhibitor of tubulin and various cancer cell lines and inhibits tubulin polymerisation and K562 cell growth with an IC50 of 0.73 μM and...
T10826	CK-666	442633-00-3	99.33%
T10826	CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, block...
T9504	MAP4343	511-26-2	99.32%
T9504	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, ...