Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.

Cat. No.	Product name	CAS No.	Purity
T21470L	Davunetide acetate		99.78%
T21470L	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing pept...
T17228	Sabizabulin	1332881-26-1	99.76%
T17228	Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin...
T5749	10-Deacetyl-7-xylosyl paclitaxel	90332-63-1	99.76%
T5749	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used ...
T1992	Mertansine	139504-50-0	99.76%
T1992	Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through...
T9595	LP-261	915412-67-8	99.76%
T9595	LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
T22262	Ansamitocin p-3	66584-72-3	99.73%
T22262	Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
T61360	ARN25068	2649882-80-2	99.71%
T61360	ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses...
T4029	BTB-1	86030-08-2	99.71%
T4029	BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
TN2256	Taccalonolide B	108885-69-4	99.69%
TN2256	Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits ...
T77651	Tubulin polymerization-IN-47	2834087-62-4	99.69%
T77651	Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer c...
T70407	Cemadotin free base	159776-69-9	99.69%
T70407	Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks mitosi...
T23889	CID-663143	578723-96-3	99.68%
T23889	CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.
T7800	TN-16	33016-12-5	99.68%
T7800	TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)
T6345	Tirbanibulin	897016-82-9	99.67%
T6345	Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate a...
T19720	Colcemid	477-30-5	99.66%
T19720	Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
T16031	McMMAF	863971-19-1	99.65%
T16031	McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC link...
T0190	Vinorelbine	71486-22-1	99.64%
T0190	Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the ar...
T5170	KHS101 hydrochloride	1784282-12-7	99.6%
T5170	KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
T4077	PE859	1402727-29-0	99.6%
T4077	PE859 is a potent inhibitor of both tau and Aβ aggregation.
T4232	VCMMAE	646502-53-6	99.58%
T4232	VCMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity.