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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13228 Tubulysin D 309935-57-7 98%
Tubulysin D
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.
T22118 NQTrp 185351-19-3 98%
NQTrp
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
T7003 Leucomethylene blue mesylate 1236208-20-0 99.99%
Leucomethylene blue mesylate
Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and fronto...
T2773 Vindoline 2182-14-1 99.97%
Vindoline
Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
T6272 Fosbretabulin Disodium 168555-66-6 99.96%
Fosbretabulin Disodium
Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretab...
T2220 2-Methoxyestradiol 362-07-2 99.95%
2-Methoxyestradiol
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by red...
T0938 Thiabendazole 148-79-8 99.94%
Thiabendazole
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
T0651 N-Phenylbenzylamine 103-32-2 99.93%
N-Phenylbenzylamine
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
T9812 Tubulin inhibitor 24 2415761-65-6 99.89%
Tubulin inhibitor 24
Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.
T25384 Erbulozole 124784-31-2 99.88%
Erbulozole
Erbulozole (R 55104) is a potent synthetic microtubule inhibitor with anti-invasive, anti-tumour and radiosensitising activity that induces Wernicke's encephalop...
T6213 Vinorelbine ditartrate 125317-39-7 99.86%
Vinorelbine ditartrate
Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.
T77647 Tubulin polymerization-IN-43 2773345-90-5 99.85%
Tubulin polymerization-IN-43
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule net...
T15576 Indibulin 204205-90-3 99.83%
Indibulin
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin as...
T60086 TTBK1-IN-2 2765453-51-6 99.83%
TTBK1-IN-2
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1...
T21470L Davunetide acetate 99.78%
Davunetide acetate
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing pept...
T17228 Sabizabulin 1332881-26-1 99.76%
Sabizabulin
Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin...
T9595 LP-261 915412-67-8 99.76%
LP-261
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
T22262 Ansamitocin p-3 66584-72-3 99.73%
Ansamitocin p-3
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
T61360 ARN25068 2649882-80-2 99.71%
ARN25068
ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses...
T4029 BTB-1 86030-08-2 99.71%
BTB-1
BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
Tubulysin D
T13228
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.
NQTrp
T22118
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
Leucomethylene blue mesylate
T7003
Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and fronto...
Vindoline
T2773
Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
Fosbretabulin Disodium
T6272
Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretab...
2-Methoxyestradiol
T2220
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by red...
Thiabendazole
T0938
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
N-Phenylbenzylamine
T0651
A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
Tubulin inhibitor 24
T9812
Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.
Erbulozole
T25384
Erbulozole (R 55104) is a potent synthetic microtubule inhibitor with anti-invasive, anti-tumour and radiosensitising activity that induces Wernicke's encephalop...
Vinorelbine ditartrate
T6213
Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.
Tubulin polymerization-IN-43
T77647
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule net...
Indibulin
T15576
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin as...
TTBK1-IN-2
T60086
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1...
Davunetide acetate
T21470L
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing pept...
Sabizabulin
T17228
Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin...
LP-261
T9595
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
Ansamitocin p-3
T22262
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
ARN25068
T61360
ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses...
BTB-1
T4029
BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
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TargetMol