T9108 |
BI-0115
|
4929-23-1
|
99.69%
|
|
BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of ...
|
T10098 |
PGS-IN-1
|
102271-49-8
|
99.67%
|
|
PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).
|
T5200 |
Indirubin-3'-monoxime
|
160807-49-8
|
99.65%
|
|
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin...
|
T8356 |
FPL 62064
|
103141-09-9
|
99.64%
|
|
FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetas...
|
T3879 |
Silychristin
|
33889-69-9
|
99.64%
|
|
Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and l...
|
TN2068 |
Picrinine
|
4684-32-6
|
99.6%
|
|
Picrinine is an akuammiline alkaloid extracted from the leaves of Alstonia scholaris. It exhibits anti-inflammatory activity by inhibiting 5-lipoxygenase.
|
TJS0315 |
4-Methyldaphnetin
|
2107-77-9
|
99.57%
|
|
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl rad...
|
T0477 |
Zileuton
|
111406-87-2
|
99.56%
|
|
Zileuton (A 64077) is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which cataly...
|
T25737 |
Linetastine
|
159776-68-8
|
99.55%
|
|
Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in ...
|
T68037L |
CBS-1114 HCl
|
33244-00-7
|
99.53%
|
|
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl ma...
|
T6568 |
Licofelone
|
156897-06-2
|
99.49%
|
|
Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhib...
|
T3S0153 |
Xanthatin
|
26791-73-1
|
99.39%
|
|
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSC...
|
T6S1699 |
Shogaol
|
555-66-8
|
99.39%
|
|
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory prop...
|
T22398 |
Phenidone
|
92-43-3
|
99.34%
|
|
Phenidone (1-phenyl-3-pyrazolidinone) is a dual inhibitor of cyclooxygenases and lipoxygenases that ameliorates rat paralysis in experimental autoimmune encephal...
|
T62606 |
ALOX15-IN-2
|
2764818-23-5
|
99.32%
|
|
ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate...
|
T4347 |
ML355
|
1532593-30-8
|
99.26%
|
|
ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
|
TJS2190 |
Nordihydroguaiaretic acid
|
500-38-9
|
99.2%
|
|
Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ...
|
T77528 |
5-LOX-IN-2
|
179691-97-5
|
99.18%
|
|
5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 μM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduc...
|
TN5634 |
Aureusidin
|
38216-54-5
|
99.18%
|
|
Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.
|
T1401 |
Meclofenoxate hydrochloride
|
3685-84-5
|
99.04%
|
|
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
|