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Lipase

Lipase refers to a class of enzymes that catalyze the hydrolysis of fats. Some lipases display a broad substrate scope including esters of cholesterol, phospholipids, and of lipid-soluble vitamins, and sphingomyelinases; however, these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to an oil-water interface". Lipases perform essential roles in the digestion, transport and processing of dietary lipids in most organisms.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T11199 Endothelial lipase inhibitor-1 1466427-02-0 97.38%
Endothelial lipase inhibitor-1
Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.
T4052 KML29 1380424-42-9 98%
KML29
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It ha...
T5353 ABX-1431 1446817-84-0 98%
ABX-1431
ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
T9687 MAGL-IN-4 2135785-20-3 98%
MAGL-IN-4
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
Endothelial lipase inhibitor-1
T11199
Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.
KML29
T4052
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It ha...
ABX-1431
T5353
ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
MAGL-IN-4
T9687
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
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TargetMol