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IL Receptor

Interleukin receptors are a family of cytokine receptors for interleukins. They belong to the immunoglobulin superfamily.There are two main families of Interleukin receptors, Type 1 and Type 2.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T36527 IL-4-inhibitor-1 1332184-63-0 98.26%
IL-4-inhibitor-1
IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It i...
T3S0006 (E)-Ferulic acid methyl ester 22329-76-6 98.22%
(E)-Ferulic acid methyl ester
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a possible inhibitor of the mitogen activated phosphor kinase pathway, it could be a potential anti-inflam...
T1273 Diacerein 13739-02-1 98.14%
Diacerein
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diace...
T9581 ARRY-797 1034189-82-6 98.12%
ARRY-797
ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
T3910 Pulchinenoside C 129741-57-7 98.04%
Pulchinenoside C
Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects.
T5680 Aloin(mixture of A&B) 8015-61-0 98%
Aloin(mixture of A&B)
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
T5779 MOSLOFLAVONE 740-33-0 98%
MOSLOFLAVONE
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
T5660 Menthone 10458-14-7 98%
Menthone
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor ne...
T6761 Ossirene 106566-58-9 98%
Ossirene
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T0947 Dexamethasone acetate 1177-87-3 98%
Dexamethasone acetate
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
TN6739 Angoline 21080-31-9 97.9%
Angoline
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosp...
T60739L Y13g dihydrochloride T60739L 97.81%
Y13g dihydrochloride
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are rela...
T5S0167 Atractylenolide I 73069-13-3 97.55%
Atractylenolide I
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reductio...
T8867 RO2959 Hydrochloride 1219927-22-6 97.42%
RO2959 Hydrochloride
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T36347 Ac-YVAD-CMK 178603-78-6 97.08%
Ac-YVAD-CMK
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
T14075 A-802715 107767-58-8 96.29%
A-802715
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation...
T21644L AF 12198 Acetate T21644L 95.27%
AF 12198 Acetate
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
T13666 Dupilumab 1190264-60-8 95.00%
Dupilumab
Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor...
T38105 Ixekizumab 1143503-69-8 95.00%
Ixekizumab
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
TN1576 Diallyl disulfide 2179-57-9 95%
Diallyl disulfide
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
IL-4-inhibitor-1
T36527
IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It i...
(E)-Ferulic acid methyl ester
T3S0006
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a possible inhibitor of the mitogen activated phosphor kinase pathway, it could be a potential anti-inflam...
Diacerein
T1273
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diace...
ARRY-797
T9581
ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
Pulchinenoside C
T3910
Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects.
Aloin(mixture of A&B)
T5680
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
MOSLOFLAVONE
T5779
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
Menthone
T5660
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor ne...
Ossirene
T6761
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
Dexamethasone acetate
T0947
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
Angoline
TN6739
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosp...
Y13g dihydrochloride
T60739L
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are rela...
Atractylenolide I
T5S0167
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reductio...
RO2959 Hydrochloride
T8867
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
Ac-YVAD-CMK
T36347
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
A-802715
T14075
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation...
AF 12198 Acetate
T21644L
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
Dupilumab
T13666
Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor...
Ixekizumab
T38105
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...
Diallyl disulfide
TN1576
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
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TargetMol