Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T13564 | AZ7550 | 1421373-99-0 | 97.07% |
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AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM). | ||||
T13564L | AZ7550 hydrochloride | 2309762-40-9 | 97.07% |
|
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM). | ||||
T11593 | I-OMe-Tyrphostin AG 538 | 1094048-77-7 | 96.66% |
|
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated sig... | ||||
TP2209L | Xenin 8 acetate | TP2209L | 95.54% |
|
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%)... | ||||
T3621 | Brigatinib | 1197953-54-0 | 100% |
|
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor. | ||||
T9030 | SU4984 | 186610-89-9 | 100% |
|
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1). | ||||
T9980 | AVJ16 | 98% |
|
|
AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation. | ||||
T76727 | Teprotumumab | 1036734-93-6 | 98% |
Teprotumumab
|
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. T... | ||||
T76795 | Xentuzumab | 1417158-65-6 | 98% |
|
Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits IGF1 and IGF2 growth-promoting signalling and inhibits AKT activ... | ||||
T76810 | Ganitumab | 905703-97-1 | 98% |
Ganitumab
|
Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low... | ||||
TP1125 | Insulin(cattle) | 11070-73-8 | 98% |
|
Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells。It has often been used as growth supp... | ||||
T6S1487 | Ginsenoside Rg5 | 186763-78-0 | 98% |
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1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production a... | ||||
T17267 | XL228 | 898280-07-4 | 98% |
|
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively). | ||||
TN7108 | Urolithin C | 165393-06-6 | 98% |
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Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway. | ||||
T6057 | URMC-099 | 1229582-33-5 | 98% |
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URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)... |