T23095 |
NU 9056
|
1450644-28-6
|
95.36%
|
|
NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM. NU 9056 blocks DNA damage response and inhibits protein a...
|
T78815 |
MOZ-IN-3
|
|
98%
|
|
MOZ-IN-3 (Compound 6j), a potent KAT6A (MOZ) acetyltransferase inhibitor with an IC50 of 30 nM, exhibits antitumor activity against multiple myeloid leukemia cel...
|
T79086 |
MC4171
|
|
98%
|
|
MC4171 (compound 34), a selective KAT8 inhibitor (IC50=8.1 µM), demonstrates moderate antiproliferative activity at micromolar concentrations in various cancer c...
|
T79131 |
KAT modulator-1
|
1314006-43-3
|
98%
|
|
KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].
|
T4362 |
WM-8014
|
2055397-18-5
|
99.95%
|
|
WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.
|
T12098 |
MOZ-IN-2
|
2055397-88-9
|
99.89%
|
|
MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 μM).
|
T0065 |
Acetaminophen
|
103-90-2
|
99.88%
|
|
Analgesic antipyretic derivative of acetanilide. Acetaminophen (APAP) has weak anti-inflammatory properties and is used as a common analgesic, but may cause live...
|
T60558 |
NSC 694623
|
907957-34-0
|
99.87%
|
|
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows...
|
T7856 |
Naphthol AS-E
|
92-78-4
|
99.85%
|
|
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
|
T6908 |
NSC 228155
|
113104-25-9
|
99.84%
|
|
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
|
T3499 |
Remodelin
|
949912-58-7
|
99.78%
|
|
Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
|
TN1150 |
Procyanidin B3
|
23567-23-9
|
99.71%
|
|
Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity.
|
T8344 |
CPTH2
|
357649-93-5
|
99.5%
|
|
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
|
T5468 |
YF-2
|
1311423-89-8
|
99.19%
|
|
YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM...
|
T6584 |
MG 149
|
1243583-85-8
|
99.1%
|
|
MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
|
T3969 |
I-CBP112
|
1640282-31-0
|
99.1%
|
|
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.
|
T1516 |
Curcumin
|
458-37-7
|
98.98%
|
|
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide...
|
T6389 |
Anacardic Acid
|
16611-84-0
|
98.84%
|
|
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial...
|
T6668 |
SGC-CBP30
|
1613695-14-9
|
98.64%
|
|
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
|
T11807 |
L002
|
321695-57-2
|
98.59%
|
|
L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 acti...
|